DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and CG5592

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	126/549 - (22%)
Similarity:	228/549 - (41%)	Gaps:	86/549 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWC------GIPELQDTNWTHAQKREI 89
            :|..|.|...:.|..:....|..|.......:..||.:.||      |:||.:       ||...
  Fly    16 IGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESE-------QKNRG 73

  Fly    90 VAKGLDSG--GCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCR---VKGQHEFAHPETT 149
            :.|..|..  .|.:::        :.|::  |.|....|...|  :.|.   :..:.|.  |..:
  Fly    74 IPKKQDGSFENCFMYN--------VPYDS--NATNDANQTRSP--IPCNNGWIYDRKEV--PYES 124

  Fly   150 FVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPW 214
            ...:::..||:....|.:.|...:|...|...||.:.|..||..:..|..:..::|.........
  Fly   125 IATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD 189

  Fly   215 YSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWM-SIAFSASYPVGMIILAIVGYVIQPWR 278
            :..|.|.||..|.:.:..|.|.:.:.:||:.:|:|:.: ::|.:..:.:|..:|..:.|||..||
  Fly   190 FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWR 254

  Fly   279 HLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKS 343
            |..:.:.:|.:.:||...|..|||.||::..:.||..:::         :.|..|..::.|::..
  Fly   255 HYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVM---------KEAAKANGKIISEEVW 310

  Fly   344 LEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVS---- 404
            .|..|.:    :||          :||.::.:. :.|..:|........:|.|....::|:
  Fly   311 SEMRECY----ELK----------FANEQLGKQ-YTSLDLFKTFPRLVVLTILIVTWMTVALAYD 360

  Fly   405 ---RYLYIIGT---------GLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPA-- 455
               |.:.|:.|         .||:||:.:||:::|...||:.....:.|....|.|.|..:..
  Fly   361 AHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHW 425

  Fly   456 -GSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGA 519
             .||..|.|     ||..:..|:|...:.:|:.||.:|...|...:....:|::.:|.   ||..
  Fly   426 NASTAAIAA-----RFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPL---VLST 482

  Fly   520 LGWY--IPTTICGCCVLVAGLLTLTLPET 546
            ..:|  :|..|.....::..|:.|.||||
  Fly   483 HRYYRPLPMFIITLVSVIGALIILFLPET 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	93/398 (23%)
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	126/548 (23%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	93/399 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990