Protein Alignment CG6356 and Slc22a20

DIOPT Version :9

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 612
• Identity: 156/612 - (25%)
• Similarity: 247/612 - (40%)
• Gaps: 140/612 - (22%)

  Fly    25 TKQLEVVGSGGAFVWAIFFLCVTP-------NILNGF----------HVSSYT----------LL 62
            |..|:.:|..|.|......|.:.|       ..|..|          |.::||          |.
Mouse     4 TDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEPTTNVSGVWLR 68

  Fly    63 GHLPDDQWCGIPE----LQDTNWT----HAQKREIVAKGLDSGGCTVWDWNYGHLAKMSYEAALN 119
            ..:|.:|. |.||    ..:..|.    :|....:..:|...|      |.|..
Mouse    69 AAIPLNQH-GDPEPCRRYVEPQWALLKPNASSHGVATEGCKDG------WVYDR----------- 115

  Fly   120 YTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGI 184
                  .|.|                  :|.|.:|||.|:....|..||.....|...|:..||.
Mouse   116 ------SIFP------------------STIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGG 156

  Fly   185 LADKFGRKSSF--------TLGAAFFIVGSF--FCTFSPWYSLFLAGRFALGAASSGLFYPAFTM 239
            |||:.|||:..        ..|||...||||  :|.|          ||.:|...||:...:.::
Mouse   157 LADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYCVF----------RFLMGMTFSGIILNSLSL 211

  Fly   240 IVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRW 304
            :||.:..:.|:...|....|:.:|.:|||.|.|:|:|||.||.|::.|.|:..|..:.:.||.||
Mouse   212 VVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRW 276

  Fly   305 LITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVA------SDKKSLEPEEGFSFGQ------KLK 357
            |:.                |.:.|.||....:||      ::.:.|..|...|:.|      :..
Mouse   277 LLL----------------HGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEFASVRTS 325

  Fly   358 NGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLV 422
            |    ||::|:....:||:......::...|::||..|::.....:|.||.....|::|||:.||
Mouse   326 N----SILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLV 386

  Fly   423 PVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELY 487
            ....:.:.|||.|.....:..|:.::..:.:|....|.....|.||:..:::::..|.|:|.|||
Mouse   387 ATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTGELY 451

  Fly   488 PTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGL-----LTLT----L 543
            ||:||...:|..|..|.:|.:.|| ::..||.:...:|....|...::||:     ||.|    |
Mouse   452 PTEIRQMGMGFASVNARLGGLVAP-LITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVPL 515

  Fly   544 PETGTGKLSDKVESSASSTPTEPAEKQ 570
            .|| ...:..:|:...|...||...::
Mouse   516 VET-IAAMERRVKQGRSKRDTEQKSEE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	116/407 (29%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	148/579 (26%)
		MFS	138..507	CDD:119392	113/399 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		4/16 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950