DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and CarT

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster

Alignment Length:	575	Identity:	143/575 - (24%)
Similarity:	251/575 - (43%)	Gaps:	61/575 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PEKNRELISEESMKDLLTKQLEVVGSGGAF-VWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWC 71
            ||....:.....:.||    |..:|..|.: ...:|.:|:...|..||...:...:...|||.||
  Fly    24 PESQPSVDEAFDLDDL----LPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWC 84

  Fly    72 GIPELQDTNWTHAQKREIVAKGLDS-----GGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPA 131
            .||||.|.. ...:|...:.|.||:     ..|..:..|:..|.:...|      ..||.:.|.|
  Fly    85 RIPELLDLP-LEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEE------DDLTTMEPNA 142

  Fly   132 E---VSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKS 193
            .   :.|....::..:...::.|.|:||.||:.|..|....:::.|...|.:.||:|.|:.||:.
  Fly   143 SWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRL 207

  Fly   194 SFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSA 258
            |:.:..|..:.||...:.|..:..:...|..:|.....::...|.:.:|.:...:||::::....
  Fly   208 SYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCT 272

  Fly   259 SYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKIL----- 318
            .|..|:::|:.|.|:.:.|..|....::|.....|..::|.||||||:...|.:...|||
  Fly   273 FYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAK 337

  Fly   319 -----FRQPSHYQIQPAVAAPSQVASDKKSLEPEEGFSFGQ----KLKNGPLKSI---IELYANS 371
                 |.:..|.:::      :|:..||...:.::..:.|.    :..|..||:|   :..:||.
  Fly   338 VNGREFPEAVHLKLE------AQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANE 396

  Fly   372 KVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTT 436
            .|            ...||||..|| ..|..||.:|    :.:|::||||.....:...|||...
  Fly   397 TV------------YLGLSYYGPAL-GTNQYVSFFL----SAVVELPSYLCCWYFMDTWGRRWPL 444

  Fly   437 MFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCST 501
            ....:..||:.::.:.:|..:....:...::.:..:||::.::..:..||||||:|...:|..|.
  Fly   445 SLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSY 509

  Fly   502 FAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVE 556
            ...:|.|..|::. .||.....:|..|.|...::.|:..|.||||...:|...:|
  Fly   510 IGGLGLIGIPFIT-YLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIE 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	94/393 (24%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	137/547 (25%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	94/392 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.060