DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and SPAC23D3.12

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_594549.1	Gene:	SPAC23D3.12 / 2541484	PomBaseID:	SPAC23D3.12	Length:	559	Species:	Schizosaccharomyces pombe

Alignment Length:	474	Identity:	114/474 - (24%)
Similarity:	174/474 - (36%)	Gaps:	128/474 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 SLGKFCGSFSFGILADKFGRKSSFTLGAAFFIV------------------GSFFCTFSPWYSLF 218
            ::|...|...||.:.|.||||  |..|....:|                  |.....|: |
pombe    98 NIGNVFGQILFGFMGDFFGRK--FVYGKEMIVVIIATVLVIALPKSIPTPLGKMMWIFA-W---- 155

  Fly   219 LAGRFALGAASSGLFYPAFTMIVENICLKHR-SWMSIAFS-------ASYPVGMIILAIVGYVIQ 275
               |:.||....|.:..:.|:..|...|..| :.:||.||       |...|.:|:||.....:.
pombe   156 ---RWLLGLGIGGDYPMSATITSERSLLSRRGTLLSIVFSFQGFGTLAGAIVTIILLACFEKPLN 217

  Fly   276 P----------WRHLQLALT-IPSLLLILNCYLMSESPRW--------LITNQRY----DRVYKI 317
            .          || ||:.|. :|:||:::....|.||..:        ...|..|    |...|.
pombe   218 QRGEYTKLEGVWR-LQMGLALVPALLVLIPRLTMKESKSYEQSKALNKYTDNDTYIADDDEPKKD 281

  Fly   318 LFRQPSHYQIQPAVAAPSQVAS-----DKK-----SLEPEEGFSFGQKLKNGPLKSIIELYANSK 372
            ........||....::.|...|     ||:     :.|...||              ||.::...
pombe   282 NQNVVEEKQINLTTSSDSHPTSTEDFGDKRASTVPTSENTSGF--------------IEYFSQWH 332

  Fly   373 VRRMIFASYFMFCVTSLSYYVTALN------AANLSVSRYLY------IIGTGLVDI----PSYL 421
            ..:.:.|:...:.:..:::|...||      |...|..:..|      .||..::.|    |.|.
pombe   333 HFKHLLATAVSWFLLDIAFYGVNLNQSVILKAIGFSSGKNEYHTLMRGAIGNLIIAIAGYVPGYW 397

  Fly   422 VPVIMLRFTGRR-LTTMFLFLWTGVSLLLVLAVPAGSTTW-----------IVAFAMLGRFGISA 474
            ..|.::...||: :....||: ||    |:.|:.|||  |           .|.......||.:|
pombe   398 FTVFLVEKLGRKWIQLQGLFI-TG----LMFAILAGS--WDTISTGGRFACFVIAQFFSNFGPNA 455

  Fly   475 TYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWY--IPTTICGCCVLVAG 537
            |   ..||.||::|.::|.:|.|..:.....|:|.|..:.:.|.::..|  :....|| |:..|.
pombe   456 T---TFLYPAEVFPARVRGTAHGLSAALGKCGAILASLLFNFLTSVIGYGNVMWIFCG-CMWGAI 516

  Fly   538 LLTLTLPETGTGKLSDKVE 556
            ..||.||||   |:.|..|
pombe   517 FFTLLLPET---KMRDADE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	107/460 (23%)
SPAC23D3.12	NP_594549.1	2A0109	27..536	CDD:129965	114/474 (24%)
SPAC23D3.12	NP_594549.1	MFS	48..523	CDD:119392	107/460 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	2	2.000