DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and SPBC1683.01

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_595057.1	Gene:	SPBC1683.01 / 2540085	PomBaseID:	SPBC1683.01	Length:	573	Species:	Schizosaccharomyces pombe

Alignment Length:	467	Identity:	106/467 - (22%)
Similarity:	180/467 - (38%)	Gaps:	105/467 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 SLGKFCGSFSFGILADKFGRKSSFTLGAAFFIV-----------GSFFCTFSPWYSLFLAGRFAL 225
            ::|...|...||.:.|.||||  |..|....||           .|.....|....:| ..|:.|
pombe   103 NIGNIFGQLMFGFMGDFFGRK--FVYGKEMIIVIIATILLIAMPKSIHSPLSKMMWVF-CWRWLL 164

  Fly   226 GAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVI-----QP--------- 276
            |....|.:..:..:..|...|..|..:.....|....|.:..|||..::     .|
pombe   165 GVGIGGDYPMSAAITSERSKLNRRGTLISLIFAFQGFGTLAGAIVTIILLGCFEHPLNREGHYRK 229

  Fly   277 ----WRHLQLALT-IPSLLLILNCYLMSESPRWLITNQ--RYDRVYKILFRQPS---HYQIQPAV 331
                || ||..|. :|::.:::...:|.|:.::..:.|  ..|.      |.|.   :::....|
pombe   230 LEGVWR-LQFGLALVPAIGVLIPRLMMEETQKFKNSQQLNSGDN------RDPKTSLNFEDDELV 287

  Fly   332 AAPSQVASDKKSLEPEEGF-SFGQKLKNGPLKSIIELY--ANSKVRRMIFASYFM-------FCV 386
            ..||......:..|..|.: |....::|.| ::|.:.:  .::...|..|..||.       ...
pombe   288 KNPSVTKGHPEIHESSENYLSRSNTVENEP-ENIEKQFESVSAPANRSGFIQYFRQWHHFKHLLG 351

  Fly   387 TSLSYYV--TALNAANLSVSRYLYIIG--TGLVD-------------------IPSYLVPVIMLR 428
            ||:.:::  .|....||:.|..|..||  :|..:                   :|.|...|.::.
pombe   352 TSVCWFLLDIAFYGVNLNQSVILKNIGFSSGTNEYRTLMKNAIGNLIIAVAGYVPGYWFNVFLVE 416

  Fly   429 FTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTW-----------IVAFAMLGRFGISATYSVVTLY 482
            ..||:...:..|:.||    |:.|:.||  .|           .|...:...||.::|   ..:|
pombe   417 ILGRKWIQLQGFVITG----LMFAILAG--RWNEISTGGRFACFVIAQLFSNFGPNST---TFIY 472

  Fly   483 TAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWY--IPTTICGCCVLVAGLL-TLTLP 544
            .||::|.::|.:|.|..:.....|:|.|..:.:.|.::..|  :....|||  :..|:| ||.||
pombe   473 PAEVFPARVRGTAHGISAALGKCGAILASLLFNFLTSIIGYGNVMWIFCGC--MWGGILFTLLLP 535

  Fly   545 ETGTGKLSDKVE 556
            || .|:.:|:::
pombe   536 ET-KGRDADEID 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	100/453 (22%)
SPBC1683.01	NP_595057.1	2A0109	27..547	CDD:129965	106/467 (23%)
SPBC1683.01	NP_595057.1	MFS	48..535	CDD:119392	100/453 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	2	2.000