DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and SPCC2H8.02

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_587972.1	Gene:	SPCC2H8.02 / 2538980	PomBaseID:	SPCC2H8.02	Length:	583	Species:	Schizosaccharomyces pombe

Alignment Length:	504	Identity:	110/504 - (21%)
Similarity:	184/504 - (36%)	Gaps:	135/504 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 RTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSP-----------WYSL 217
            |.....:.::|...|...||.|.|.||||..:.......|:.:......|           |...
pombe    85 RGVVNAATNIGNIMGQLLFGFLGDFFGRKFVYGKEMMVVIIATILIICLPDRIPTPTAKMMWLFA 149

  Fly   218 FLAGRFALGAASSGLFYPAFTMIVENICLKHR-----SWMSIAFS-------ASYPVGMIILAIV 270
            |   |..||....| .||....|.....|.:|     :|:   ||       |.....:||||..
pombe   150 F---RVMLGIGIGG-DYPMSASITSEQSLINRRGALLAWI---FSNQGWGTLAGCVATLIILACF 207

  Fly   271 GYVIQP----------WRHLQLALTI-PSLLLILNCYLMSESPRWLITNQR---------YDRVY 315
            ...:..          || :|..:.: |::::::....|.||.::  .|.:         .|...
pombe   208 EKPLNDRGEYTKLNGVWR-IQFGIALFPAVIVLIPRLRMQESEQF--KNSKNMKSPGEGDLDSAS 269

  Fly   316 KIL---FRQPSHYQIQPAVAAPSQVA-SDKKS-----LEPEEGFSFGQKLKNGPLKSIIELYANS 371
            :|.   |::......:...::||..: ||||:     :.|....:........|..:.:|.....
pombe   270 QIELHDFKKKESLTAEFTTSSPSTASLSDKKNPGSVHIRPNNEVAPSSAPSRAPSTTSVESNTEG 334

  Fly   372 KVRRM----IFASYF--------------MFCVTSLSYYVTALNAA--------NLSVSRYLYI- 409
            |...:    .|.|||              .:.:..:::|...||.:        |..|:.|..:
pombe   335 KESDIQTGSSFVSYFKEWRHAKLLIGSALSWFLLDIAFYGINLNQSVILQEMGFNKGVNEYHILQ 399

  Fly   410 ---IGTGLVD----IPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAG--STTW----- 460
               ||..::.    ||.|.|.|:::...||:        |..:...|:..:..|  :.||
pombe   400 KNAIGNLIIAVAGYIPGYWVSVVLIEVMGRK--------WIQIQGFLICCLLFGVLAGTWETIST 456

  Fly   461 -----IVAFA-MLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVL-- 517
                 .||.| ....||.:.|..|:   .||::|:::|..:.|.|:.....|:|.:..:.:.|
pombe   457 GGRFACVALAQFFFNFGPNTTCFVI---PAEVFPSRVRAFSHGICAACGKAGAILSALLFNKLTE 518

  Fly   518 ----GALGWYIPTTICGCCVLVAG-LLTLTLPETGT--GKLSDKVESSA 559
                |.:.|    ...||  :||| ::||.||||..  ..|.|::|.:|
pombe   519 VIGFGNVLW----IFFGC--MVAGAVVTLILPETANRDADLIDRLEIAA 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	101/482 (21%)
SPCC2H8.02	NP_587972.1	2A0109	38..557	CDD:129965	108/498 (22%)
SPCC2H8.02	NP_587972.1	MFS	42..544	CDD:119392	102/485 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	2	2.000