DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and Slc22a29

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_766364.1	Gene:	Slc22a29 / 236293	MGIID:	3605624	Length:	551	Species:	Mus musculus

Alignment Length:	568	Identity:	138/568 - (24%)
Similarity:	238/568 - (41%)	Gaps:	78/568 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SMKDLLTKQLEVVGSGGAF-VWAIFFLCVTPNILNGF---HVSSYTLLGHLPDDQWCGIPELQDT 79
            |.::||.:    |||.|.| :..|.||.    :||..   |:........:|:.: |.:|.|.:.
Mouse     2 SFQELLNQ----VGSLGRFQILQIVFLF----LLNAIVVPHIGMENFTAAIPNHR-CWVPILDND 57

  Fly    80 NWTHAQKREI-------VAKGLDSG----GCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEV 133
            ..:....|.:       ::..|||.    .|..:.....||        |:..|..:.:|.|...
Mouse    58 TASDNGSRILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHL--------LHLNGTFSNVSEPDTE 114

  Fly   134 SCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLG 198
            .|.....::.::..:|.|.:|||.|:.....:..:.|..:|.|.|....|.|:|:||||...|..
Mouse   115 PCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRFGRKFILTCA 179

  Fly   199 AAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVG 263
            ...|.:......|:|.:.::.:.||..|.:...:...:..:::|....|..:.|::..|.:..:|
Mouse   180 LLQFAITETCVAFAPSFFIYCSLRFLAGMSVEPISVNSHLLMLEWTSPKFLAMMAVLSSCAPNIG 244

  Fly   264 MIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQ-- 326
            .:|||.:.::.:.|.||||.::.|....::....:|||.||||...:..:..|.| |:.:|..
Mouse   245 FMILAGLAFLFRIWHHLQLTMSAPIFFFLILTRWLSESARWLILINKPQKGLKEL-RKVAHMNGM 308

  Fly   327 ----------IQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASY 381
                      ::.::.|..:.|..|.||.                    :|:..|.:|:.|....
Mouse   309 KNSGDLTMEIVRTSMKAELEAAKTKPSLR--------------------DLFHTSILRKRICVLS 353

  Fly   382 FMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVI---MLRFTGRRLTTMFLFLWT 443
            |:....::|....|::..:||.:   .|:...|:...:.||.||   :|...|||:|.:.|....
Mouse   354 FIRLFFTVSIIGLAVHLQHLSSN---IILLQFLISALAILVSVIGPFVLNHIGRRITYLVLMSLR 415

  Fly   444 GVSLLLVLAVPAGSTTWIVAFAMLGRFGISA-TYSVVTLYTAELYPTQIRNSALGTCSTFAHVGS 507
            |:.:::.:.||....|..:..|.|.. |||: ...|..|:|.||.||.:|.:|||....|.:.|.
Mouse   416 GIFIMIAVFVPQEMQTLRIIMATLAG-GISSLCVGVSHLHTNELLPTTLRATALGVIGFFGNSGL 479

  Fly   508 ISAPYVVDVLGALGWY--IPTTICGCCVLVAGLLTLTLPETGTGKLSD 553
            ..:|..:.|   ..:|  :|....|...:........||||....|.|
Mouse   480 FLSPLFMLV---ATYYANLPWIFYGGFSIFNAFTVFLLPETKNQPLPD 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	96/394 (24%)
Slc22a29	NP_766364.1	MFS_OAT	109..515	CDD:340932	105/433 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940