Protein Alignment CG6356 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 533
• Identity: 144/533 - (27%)
• Similarity: 236/533 - (44%)
• Gaps: 28/533 - (5%)

  Fly    31 VGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKGLD 95
            :|..|.|...||||.....|.|||:..|...|...|:.: |.:|  ...|.:.|.:...:.....
Mouse    11 LGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHR-CLVP--HTVNLSSAWRNHSIPLETK 72

  Fly    96 SGGCTVWDWNYGHLAKMSYEAALNY-TGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCD 159
            .|...........||.::..:.|.. .|....:....:.||....:::.....:|.|.:|||.|.
Mouse    73 DGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCK 137

  Fly   160 RSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFA 224
            ...:.........:|...|||..|.|:|:||||:...|........||...||..:.:|......
Mouse   138 DDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVL 202

  Fly   225 LGAASSGLFYPAFTMIVENICLKHR-SWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPS 288
            :|......:..||.:..|.:....| .:.::.....|..|.::|.:..|.|:.||.|.||||:|.
Mouse   203 VGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPG 267

  Fly   289 LLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQV-----ASDKKSLEPEE 348
            :|.....:.:.|||||||:..|.... :::.|:.:...   .:.|||.:     ..|..|.:|:
Mouse   268 VLCGALWWFIPESPRWLISQGRIKEA-EVIIRKAAKIN---GIVAPSTIFDPSELQDLNSTKPQ- 327

  Fly   349 GFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTG 413
                        |..|.:|.....:|.:...|..::...|:.|:..:|:..||....|:......
Mouse   328 ------------LHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLA 380

  Fly   414 LVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSV 478
            .|::|:|::..::|::..||.:........|..||.:..||:.......|..|:|:|||::.||:
Mouse   381 AVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSM 445

  Fly   479 VTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTL 543
            |.:||||||||.:||..:|..||.:.:|||.:||.| .|||...::|..:.|...::..:|||..
Mouse   446 VYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFV-YLGAYDRFLPYILMGSLTILTAILTLFF 509

  Fly   544 PETGTGKLSDKVE 556
            ||:....|.|.::
Mouse   510 PESFGVPLPDTID 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS_SLC22	140..544	CDD:340875	115/409 (28%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	143/528 (27%)