DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and C46C2.2

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_501604.2	Gene:	C46C2.2 / 177744	WormBaseID:	WBGene00008110	Length:	520	Species:	Caenorhabditis elegans

Alignment Length:	515	Identity:	113/515 - (21%)
Similarity:	208/515 - (40%)	Gaps:	114/515 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 CTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQ 163
            |..::.|:.:|       ..|.||  |.:|     .|..:..|.:   .::...::::.|....:
Worm    60 CLEYNENFPNL-------CANLTG--TALS-----DCHTEKSHSY---YSSAAMEFEIYCRPGWK 107

  Fly   164 RTSAQVSISLGKFCGSFSFGILADKFGRKSSF-----------TLGAAFFIVGSFFCTFSPWYSL 217
            .........:|...|:...|.:||:.|||.:|           :|.|.|..:.:|: .|.....:
Worm   108 DFRPAFVQYVGVLIGNIILGYVADQIGRKKTFILSMLIGIPSLSLSATFNSIAAFY-IFRALTGI 171

  Fly   218 FLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWR---H 279
            .:||...:|       :..|:.:|.    .|:.:....|| ::....|:|.:|......||   |
Worm   172 GIAGTMIVG-------WAYFSELVS----PHQRFKLRTFS-NWANARIMLTLVALFTGEWRLSSH 224

  Fly   280 LQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSL 344
            :...:::.:|.::.  :::.||..||....||:.......|......|:.....|.:.|:|  ::
Worm   225 VSAVISLITLAIVY--FILPESHIWLRKKGRYEEAEVSRKRIADLAGIEFVPMPPPEKAAD--NV 285

  Fly   345 EPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYI 409
            |||:..            :|..::|:.::|:.|...:.|:.||.::.|:|.|...:::.:   :.
Worm   286 EPEKAV------------NICTVFADPQLRKNILILWLMWFVTGMTAYLTDLCGGDMTKN---FW 335

  Fly   410 IGTGLVDIPSYLVPVIM------LRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLG 468
            :|..|..|...:|.:||      |.:.|||..     |....||.:|.      ...::||...|
Worm   336 VGQFLSGILLSVVRIIMGFADGYLPWMGRRFV-----LLCSQSLAIVF------FGCVIAFLFAG 389

  Fly   469 RFG---ISATYSVVTLYT-----------AELYPTQIRNSALGTCS---TFAHVGSISAPYVVDV 516
            ..|   .:|.|....::|           :||.||.:|.::..:||   .||::|:       .:
Worm   390 EKGQWYYTAVYLASFVFTSIVWEPCYLCASELMPTDVRATSTASCSIVGRFANIGA-------SM 447

  Fly   517 LGAL------GWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVESSASSTPTEPAEKQ 570
            |..|      |.::.:...|...:||..  ..|.||....| ||..:||:. |.|.|.:|
Worm   448 LSGLKTVYEPGVHMISISLGLTNVVAAY--FFLQETKNCSL-DKAGTSAAK-PAEKANEQ 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	90/419 (21%)
C46C2.2	NP_501604.2	2A0119	58..486	CDD:273328	104/494 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162844
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840