DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and UST4r

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	563	Identity:	142/563 - (25%)
Similarity:	237/563 - (42%)	Gaps:	81/563 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LEVVGSGGAF-----VWAIF-FLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPEL-------QDT 79
            |..||..|.|     |:.:| .:.|.|:|:    :.::|  ..:|..: |.:|.|       .|:
  Rat     7 LNQVGGLGRFQILQMVFVVFTSVIVVPHII----IENFT--AAIPSHR-CWVPILDNVTVSDNDS 64

  Fly    80 NWTHAQKREIVAKGLDS----GGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQ 140
            ...:..|...::..|||    ..|..:.....||        |:.....:.|:.|....|.....
  Rat    65 RILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHL--------LDLNDTFSSITEPDTEPCVDGWV 121

  Fly   141 HEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVG 205
            ::.::..:|.|.:|:|.|:.....:..::|..:|.|.|....|:|:|:||||...........:.
  Rat   122 YDRSNFHSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAIT 186

  Fly   206 SFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAF--------SASYPV 262
            .....|:|...::.:.||..|.        :...|..||.|....|.|..|        |.:...
  Rat   187 ETCAGFAPNLFIYCSLRFLAGM--------SLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSF 243

  Fly   263 GMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHY-- 325
            |.:|||.:.:..|.|.|||||:::|....::....:|||.||||...:..:..|.| ::.:|.
  Rat   244 GGMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKEL-KKVAHING 307

  Fly   326 ------QIQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMF 384
                  .|...|...|.    ||.||       ..|::..|.    :|:....:|:.|:...|:.
  Rat   308 MKKSGDNITMEVVRTSM----KKELE-------AAKMRPSPR----DLFHTPILRKQIYILSFIR 357

  Fly   385 CVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVI---MLRFTGRRLTTMFLFLWTGVS 446
            .:..||....|::..:||.:..|..|   |:.:.|.|..||   :|...|||:|.|.:....|:|
  Rat   358 LLFILSGVGVAIHLQHLSNNIELLQI---LISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGIS 419

  Fly   447 LLLVLAVPAGSTTWIVAFAMLGRFGISA-TYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISA 510
            :|..:..|....|.....||:.. |::| :|:..:|:..||.||.:|.:|.|....|.::|...|
  Rat   420 ILTAIFAPQEMETLRFIMAMMAE-GLAALSYAANSLHANELLPTTLRATARGVIGMFGNIGFFLA 483

  Fly   511 PYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSD 553
            |..: :|.:....:|....|...:::|.:.|.||||....|.|
  Rat   484 PLCM-MLASYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPD 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	104/396 (26%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	111/435 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940