Protein Alignment CG6356 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 151/621 - (24%)
• Similarity: 256/621 - (41%)
• Gaps: 103/621 - (16%)

  Fly    28 LEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLP---------------DDQW--CGIPE 75
            ||.||..|.|......|...|.:|...|......|..:|               .|.|  ..:|.
Human     7 LEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAHLPR 71

  Fly    76 LQD---------------TNWTHAQKREIVAKG-LDSGGCTV---WDWNYGHLAKMSYEAALNYT 121
            ..|               .|.|..::|:  ::| |:....||   ..|.|.|....|..|..:..
Human    72 EPDGTLSSCLRFAYPQALPNTTLGEERQ--SRGELEDEPATVPCSQGWEYDHSEFSSTIATESQV 134

  Fly   122 G----HLTQISPPAEVSCRVK---------------------GQHEFAHPETTFVA--------D 153
            |    ||       ||.||.:                     |:.:.::..:...:        :
Human   135 GIYIIHL-------EVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESLGGLLSGME 192

  Fly   154 WDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLF 218
            |||.|::.....:|......|...|:.:||.|:|:|||:....:.....:|.......|..|.:|
Human   193 WDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMF 257

  Fly   219 LAGRFALGAASSGLFYPAFTMIV--------ENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQ 275
            ...|...|:|.:|     ||:||        |.:.::||:...:..|..:..|:::||:|||:|:
Human   258 AITRTLTGSALAG-----FTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIR 317

  Fly   276 PWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASD 340
            .||.|.||:|:|....||:.:.:.||.|||:|.......::        |.:..|......|..|
Human   318 DWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHR--------YLLHCARLNGRPVCED 374

  Fly   341 KKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSR 405
            ..|.|.....:.|:::...|  |.::|:...::|.:......::...:.|||..:|:.:.|.::.
Human   375 SFSQEAVSKVAAGERVVRRP--SYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNV 437

  Fly   406 YLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRF 470
            |...:..|.|::||.|:..:.:|:.|||||.....|.|.::....|.|.:...:|....|::|:.
Human   438 YQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKA 502

  Fly   471 GISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLV 535
            ...|.::...|:|:|||||.:|.:.:|..:....:|...|| :..:|..:...:|....|...|:
Human   503 FSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAP-LAALLDGVWLSLPKLTYGGIALL 566

  Fly   536 AGLLTLTLPETGTGKLSDKVES-SASSTPTEPAEKQ 570
            |....|.||||...:|.:.::. ...|.||...|::
Human   567 AAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	102/384 (27%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	144/598 (24%)
		MFS	206..563	CDD:119392	99/372 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153684
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940