Protein Alignment CG6356 and sv2b

DIOPT Version :9

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 687
• Identity: 147/687 - (21%)
• Similarity: 221/687 - (32%)
• Gaps: 253/687 - (36%)

  Fly    63 GHLPDD-----QWCGIPELQDTNWTHAQK--------REIVAKGLDSGGCTVWDWNYGHLAKMSY 114
            ||..||     ::.|||...|.....|..        .:|:|:.::         :...|| ..|
 Frog    69 GHDEDDEIYEGEYQGIPHPDDLRQHKASSIRDEFKDPADIIAERIE---------DEEQLA-YQY 123

  Fly   115 EAALNYTGH------------LTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSA 167
            |..:...||            |..::...||.  |.|   |..|.    |:.|:...|| .:...
 Frog   124 ENIIQECGHGRFQWTLFVVLGLALMADGVEVF--VVG---FVLPS----AEKDMCLSRS-NKGML 178

  Fly   168 QVSISLGKFCGSFSFGILADKFGRKS----SFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAA 228
            .:.:.||...|:|.:|.||||.|||.    |.|:.|||    ||..:|...|.|||..|...|..
 Frog   179 GLIVYLGMMLGAFVWGGLADKVGRKKCLIISLTINAAF----SFVSSFVQGYGLFLFCRLISGFG 239

  Fly   229 SSGLFYPAFTMIVENICL----KHRSWMSIAFSASYPVGMIILAIVGYVIQP------------- 276
            ..|.....|....|.:..    :|.||:.:    .:.:|.:..|.:.:.|.|
 Frog   240 IGGSLPIVFAYFSEFLAREKRGEHLSWLCM----FWMIGAVYAAAMAWSIIPHYGWGFSMGTHYH 300

  Fly   277 ---WRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQ-- 336
               ||...:...:|.:..|:....|.||||:|:...::|..:.||  :..|.....|...|.:
 Frog   301 FHSWRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMIL--KNIHDTNMRAKGEPEKVF 363

  Fly   337 -VASDKKSLEPEE--------GFSF-----------------------GQKLKNGPLKSII---- 365
             |:..|...:|:|        |..|                       ||..||....:::
 Frog   364 TVSHIKTPKQPDEFIEIQSSTGTWFQRWFVRIMTVIKQIWENMLHCFSGQFRKNTIFLAVVWFTM 428

  Fly   366 --------------------ELYANSKVRRM---------------------------------- 376
                                |.|| |||:|.
 Frog   429 SLSYYGLTVWFPDTIRYLQDEDYA-SKVKRFTDENVKNFNFNFTLENQIHEDGEYYNDRFYKMKL 492

  Fly   377 --------IFASYFMFCVTSLS------------YYVTAL--------NAANLSVSR-------- 405
                    :|...:...|||..            :|.|.|        |..|::.|:
 Frog   493 KYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVTFSQPKEGCHID 557

  Fly   406 ---------YLYIIGTGLVDIPSYLVPVIMLRFTGR-----------RLTTMFLFLWTGVSLLLV 450
                     ||......|..:|..::..:::...||           .:...|||.....|.::
 Frog   558 FEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFLFFGNSESAMI- 621

  Fly   451 LAVPAGSTTWIVAFAMLGRFGIS-ATYSVVTLYTAELYPTQIRNSAL----GTCSTFAHVG-SIS 509
                    .|...|.     |.| |.::.:.:.|.|||||..|.:|.    |.|...|..| ||.
 Frog   622 --------GWQCLFC-----GTSIAAWNALDVVTVELYPTNKRATAFGILNGLCKLAAIFGNSIF 673

  Fly   510 APYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPET 546
            |.:|     .:...||..:....::..||::|.||||
 Frog   674 ASFV-----GITKVIPILLASTALVGGGLISLRLPET 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	115/554 (21%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	147/687 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910