DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	555	Identity:	147/555 - (26%)
Similarity:	235/555 - (42%)	Gaps:	48/555 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPEL--QDTNWTHAQKREIV 90
            ||.:|..|.|...:.|....||::..|.:|| .:..|...:..|....:  .|.|.|..::..:.
Zfish     8 LEAIGDFGLFQKLLLFALCFPNLILPFQLSS-LVFNHADTNHHCNTDWILKADPNLTKEEQLNLT 71

  Fly    91 AKGLDSGG---CTVW---DWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETT 149
            ...|..|.   |.::   |||...:    .|..||.|           .:|.....|.....|.|
Zfish    72 LPRLSDGSFNPCQMYKPVDWNLSAI----QEYGLNQT-----------TTCTDGWVHNDTIYEAT 121

  Fly   150 FVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPW 214
            .|.|:||.|:.......||.....|...|:..||..::.||||.:..:.....::.:.....||.
Zfish   122 IVTDFDLVCENVNIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLMLIFTVVTGLSPN 186

  Fly   215 YSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWRH 279
            :.::|..:|..|....|....:..:..|.|.:..||:.:........:|.::...|.|.::.||.
Zfish   187 FYVYLVSQFINGVGLGGFRINSIILASEWIGVAQRSYAACLSQVLAALGQVMFLAVVYFVRDWRL 251

  Fly   280 LQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSL 344
            .|..:..|..::::..:.:.||.|||:...|.....|:         ||.|.|.       .|..
Zfish   252 DQFIMAGPIGIVVIYIWFLPESARWLLDRGRTKDAKKL---------IQKAAAV-------NKRA 300

  Fly   345 EPEEGFSFGQKLKNGPL-KSIIELYANSKVRRMIF-ASYFMFCVTSLSYYVTALNAANLSVSRYL 407
            .||.  ...:.||..|: |..|::...|:|.|..| |..|.:|..:|:||..:||.....:..:|
Zfish   301 VPES--LVEEVLKEKPVEKGGIKILFGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKFGLDIFL 363

  Fly   408 YIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGI 472
            ..:..||.:||.:.:.:..|...||:.:.:...:..|...||.:|||..|:..|...|..|||.:
Zfish   364 TQLIFGLSEIPVHFLCMWSLEVVGRKPSLIVSLVLGGCLCLLTVAVPQNSSIAIAVLATCGRFLM 428

  Fly   473 SATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAG 537
            :|..||..:|..||:||.||.:|.|..||.|..||:.:| ||::|....:.||..:.....|.:|
Zfish   429 NAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSP-VVNMLEIFHFSIPMVVISSLALASG 492

  Fly   538 LLTLTLPETGTGKL---SDKVESSASSTPTEPAEK 569
            :....||||...:|   :::.|.......|.||.:
Zfish   493 VTAFLLPETRRTELPASTEEAEGKRKPKLTSPATR 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	103/378 (27%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	140/529 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950