Protein Alignment shps and Lao1

DIOPT Version :10

• Sequence 1: NP_651239.1
• Gene: shps / 42892
• FlyBaseID: FBgn0286199
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001100152.1
• Gene: Lao1 / 298483
• RGDID: 1310787
• Length: 519
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 98/520 - (18%)
• Similarity: 172/520 - (33%)
• Gaps: 198/520 - (38%)

  Fly    14 VLIVGGGLSGLASALKILAMESTLKVRMIEASDALGGLMGQNSTRLVDAAQQDMLALLTLIHLSP 78
            :::||.|::||.:| |:| .::..:|.::|||:.:||                  .::||
  Rat    60 IVVVGAGMAGLVAA-KLL-QDAGHEVTILEASNHIGG------------------RVVTL----- 99

  Fly    79 RRRRSISGSLRRCWDLDRGLTAMPAKFELGRYIDMLDLRMPKFRS------KRFNLRERVSNMEQ 137
              |....|     |           .||||      .:|:|:...      ::|.|  :::|..|
  Rat   100 --RNKEEG-----W-----------HFELG------PMRIPESHRIIHTYIQKFGL--KLNNFTQ 138

  Fly   138 HICHHLFFSKSRNFMLNLVQL---VCGVP---------ANEVDYDVFMSV-CSSCGGLKVLIDFY 189
            |..:..:..:...:..:.|:.   :.|.|         |.::.|.....| .|:|   ..|:..|
  Rat   139 HDNNTWYLLRGHRYRASEVKANPEILGYPLRPSEKNKTAEDLFYQAITKVKASNC---SQLLSLY 200

  Fly   190 FTYPTSFYEISTQMLIENILEQL--------QFIKIILNCRAVRLEHFKN--YVQVTD--DQ--- 239
            .:|.|..|.:...||....:|.:        .|.:.:|....:.....||  :.::|.  ||
  Rat   201 DSYSTKAYLLKEGMLSRGAVEMIGDMMNENAGFYRSLLESLRIANIFTKNDQFTEITGGFDQLPN 265

  Fly   240 ---------------------GNKH------------------TAQAAILAIPWNKVQKLHFEPR 265
                                 ||:.                  ||...|::......:.:.|:|.
  Rat   266 SLNDSLKPGTIHLGSKVERVVGNESKVEVLYRTDGPTSALYNLTADYVIISASAKATRLIAFQPP 330

  Fly   266 IPKVFLPRTTSRSGRKGRQVISQFQLRYGKSVWTDLGYS-----GNFL----SSQPMVSGHECRM 321
            :....:....|.......:||.....|:.:......|||     ..|:    .|:|...|  ..:
  Rat   331 LSPEKIRALRSVHYNSATKVIFVCNERFWEKDGIHGGYSITDRPSRFIYYPSYSRPSSKG--ILL 393

  Fly   322 SSFC------GYVLHLPEDQDEVLQDVVDLLAEHF--GEEMRQPLECQCFTDELNVAQHKPQTKP 378
            :||.      .:....|....:::.|  ||.|.|.  .||:::    .|           |:::.
  Rat   394 ASFTMDDDSFFFTALKPNQVVDIILD--DLAAVHLIPKEELKR----MC-----------PKSEV 441

  Fly   379 WHRVIWS------SSSAVGTSYRSL--------------------------MGGAVQSGFRAAVN 411
            .|   ||      .|.|..|.|:.|                          :..|::||.|||.|
  Rat   442 KH---WSLDPFTIGSYAEFTPYQFLDDLKQLSQTEGRIYFAGEHTSLPHAWIETAIKSGIRAAKN 503

  Fly   412  411
              Rat   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shps	NP_651239.1	YobN	9..409	CDD:440844	95/516 (18%)
Lao1	NP_001100152.1	YobN	51..504	CDD:440844	98/520 (19%)