Protein Alignment shps and Maoa

DIOPT Version :10

• Sequence 1: NP_651239.1
• Gene: shps / 42892
• FlyBaseID: FBgn0286199
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_387502.1
• Gene: Maoa / 29253
• RGDID: 61898
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 113/531 - (21%)
• Similarity: 208/531 - (39%)
• Gaps: 135/531 - (25%)

  Fly    13 DVLIVGGGLSGLASALKILAMESTLKVRMIEASDALGG------------------LMGQNSTRL 59
            ||:::|||:||||:| |:|: |..:.|.::||.|.:||                  .:|....|:
  Rat    15 DVVVIGGGISGLAAA-KLLS-EYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRI 77

  Fly    60 VDAAQQDMLALLT--------LIHLSPRRRRSISGSLRRCWD----LDRGLTAMPAKFELGRYID 112
            :..:::  |.:.|        |:.....:.....|:....|:    ||..        .|.|.:|
  Rat    78 LRLSKE--LGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYN--------NLWRTMD 132

  Fly   113 MLDLRMP---KFRSKRFNLRERVS--NMEQHICHHLFFSKSRNFMLNLVQLVCGVPANEVDYDVF 172
            .:...:|   .::::.....::::  ::...||   :...:|.|....|.:......:||....|
  Rat   133 EMGKEIPVDAPWQARHAQEWDKMTMKDLIDKIC---WTKTAREFAYLFVNINVTSEPHEVSALWF 194

  Fly   173 MSVCSSCGGLKVLIDFYFT-------YPTSFYEISTQMLIENILEQLQFIKIILNCRAVRLEHFK 230
            :.....|||...:  |..|       :.....::|.|::  .:|..           .|:|....
  Rat   195 LWYVRQCGGTARI--FSVTNGGQERKFVGGSGQVSEQIM--GLLGD-----------KVKLSSPV 244

  Fly   231 NYVQVTDDQ------GNKH-TAQAAILAIPWNKVQKLHFEPRIPKVFLPRTTSRSGRKGRQVISQ 288
            .|:..|||.      .::| ..:..|.|||.....|:||:|.:|    |.......|.....:.:
  Rat   245 TYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELP----PERNQLIQRLPMGAVIK 305

  Fly   289 FQLRYGKSVWTDLGYSGNFL---SSQPMV-----SGHECRMSSFCGYVLHLPED------QDEVL 339
            ..:.|.::.|....|.|..:   ...|:.     :..:..:.:..|::|....|      :|...
  Rat   306 CMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRLAKLHKDIRK 370

  Fly   340 QDVVDLLAEHFG-EEMRQPLE------CQ------CFTDELNVAQHKP--QTKPWHRV------- 382
            :.:.:|.|:..| :|...|:.      |:      |:|     |...|  .|: :.||
  Rat   371 RKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYT-----AYFPPGIMTQ-YGRVIRQPVGR 429

  Fly   383 IWSSSSAVGTSYRSLMGGAVQSGFRAA---VNAVFVVRPQVVSWKDMLVEQPKNGQDVVSAGRIR 444
            |:.:.:...|.:...|.|||::|.|||   :||:     ..|:.||:.||:|:: :||.:.....
  Rat   430 IYFAGTETATQWSGYMEGAVEAGERAAREVLNAL-----GKVAKKDIWVEEPES-KDVPAIEITH 488

  Fly   445 GLLSRLNLYNV 455
            ..|.| ||.:|
  Rat   489 TFLER-NLPSV 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shps	NP_651239.1	YobN	9..409	CDD:440844	96/480 (20%)
Maoa	NP_387502.1	YobN	11..464	CDD:440844	100/493 (20%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000250	520..522