Protein Alignment shps and IL4I1

DIOPT Version :10

• Sequence 1: NP_651239.1
• Gene: shps / 42892
• FlyBaseID: FBgn0286199
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_758962.1
• Gene: IL4I1 / 259307
• HGNCID: 19094
• Length: 589
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 91/565 - (16%)
• Similarity: 191/565 - (33%)
• Gaps: 187/565 - (33%)

  Fly    14 VLIVGGGLSGLASALKILAMESTLKVRMIEASDALGGLM----GQNSTRLVDAAQQDMLALLTLI 74
            |::||.|::||.:| |:|: ::..||.::||.:.:||.:    .||:..:.:.....|.:...::
Human    84 VIVVGAGVAGLVAA-KVLS-DAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSHRIL 146

  Fly    75 HLSPRRRRSISGSLRRCWDLDRGLTAMPAKFELGRYIDMLDLRMPKFRSKR------FNLRERVS 133
            |             :.|..|...||.. .:::...:.::.::::..:..::      :.||.:..
Human   147 H-------------KLCQGLGLNLTKF-TQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEK 197

  Fly   134 NMEQHICHHLFFSKSRNFMLNLVQLVCGVPANEVDYDVFMSVCSSCGGL-----KVLID------ 187
            .   |....::.......:.:|..|.|.....:.:....:......|.|     ::|.|
Human   198 G---HSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDG 259

  Fly   188 -FYFTYPTSFYEISTQMLIENILEQLQFIKII-------------------LNCRAVRLEHFKN- 231
             ||.::..:....|.      :.::||:.:|:                   ||...|.:....:
Human   260 FFYLSFAEALRAHSC------LSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHD 318

  Fly   232 -YVQVTDDQGNKH----TAQAAILAIPWNKVQKLHFEPRIP----------------KVFLP--- 272
             :||:......::    .|...:|......|:::.|.|.:|                ||||.
Human   319 VHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRR 383

  Fly   273 ------------RTTSRSG--------RKGRQVISQFQLRYGKSVWTDLGYSGNFLSSQPMVSGH 317
                        ..|.|..        |:|..:::.:       .|:|..
Human   384 PFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY-------TWSDAA--------------- 426

  Fly   318 ECRMSSFCGYVLHLPEDQDEVLQDVVDLLAEHFGEEMRQPLECQCFTDELNVAQH-------KPQ 375
                ::|.|.      .::|.|:..:|.:|...|..:||..:...........||       :|.
Human   427 ----AAFAGL------SREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPP 481

  Fly   376 ----------TKPWHRVIWSSSSAVGTSYRSLMGGAVQSGFRAAVNAVFVVRPQVVSWKDMLVEQ 430
                      |.|:.|:.::...   |:|..   |.|::..::|:.|...:..:.....|  ...
Human   482 ALWQTEKDDWTVPYGRIYFAGEH---TAYPH---GWVETAVKSALRAAIKINSRKGPASD--TAS 538

  Fly   431 PK-NGQDVVSAGRIRGLLS------------------RLNLYNVT 456
            |: :..|:...|.:.|:.|                  :|:|.|.|
Human   539 PEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTT 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shps	NP_651239.1	YobN	9..409	CDD:440844	79/497 (16%)
IL4I1	NP_758962.1	YobN	75..529	CDD:440844	81/507 (16%)