Protein Alignment shps and IL4I1

DIOPT Version :9

• Sequence 1: NP_651239.1
• Gene: shps / 42892
• FlyBaseID: FBgn0286199
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001244946.1
• Gene: IL4I1 / 259307
• HGNCID: 19094
• Length: 589
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 91/565 - (16%)
• Similarity: 191/565 - (33%)
• Gaps: 187/565 - (33%)

  Fly    14 VLIVGGGLSGLASALKILAMESTLKVRMIEASDALGGLM----GQNSTRLVDAAQQDMLALLTLI 74
            |::||.|::||.:| |:|: ::..||.::||.:.:||.:    .||:..:.:.....|.:...::
Human    84 VIVVGAGVAGLVAA-KVLS-DAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSHRIL 146

  Fly    75 HLSPRRRRSISGSLRRCWDLDRGLTAMPAKFELGRYIDMLDLRMPKFRSKR------FNLRERVS 133
            |             :.|..|...||.. .:::...:.::.::::..:..::      :.||.:..
Human   147 H-------------KLCQGLGLNLTKF-TQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEK 197

  Fly   134 NMEQHICHHLFFSKSRNFMLNLVQLVCGVPANEVDYDVFMSVCSSCGGL-----KVLID------ 187
            .   |....::.......:.:|..|.|.....:.:....:......|.|     ::|.|
Human   198 G---HSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDG 259

  Fly   188 -FYFTYPTSFYEISTQMLIENILEQLQFIKII-------------------LNCRAVRLEHFKN- 231
             ||.::..:....|.      :.::||:.:|:                   ||...|.:....:
Human   260 FFYLSFAEALRAHSC------LSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHD 318

  Fly   232 -YVQVTDDQGNKH----TAQAAILAIPWNKVQKLHFEPRIP----------------KVFLP--- 272
             :||:......::    .|...:|......|:::.|.|.:|                ||||.
Human   319 VHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRR 383

  Fly   273 ------------RTTSRSG--------RKGRQVISQFQLRYGKSVWTDLGYSGNFLSSQPMVSGH 317
                        ..|.|..        |:|..:::.:       .|:|..
Human   384 PFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY-------TWSDAA--------------- 426

  Fly   318 ECRMSSFCGYVLHLPEDQDEVLQDVVDLLAEHFGEEMRQPLECQCFTDELNVAQH-------KPQ 375
                ::|.|.      .::|.|:..:|.:|...|..:||..:...........||       :|.
Human   427 ----AAFAGL------SREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPP 481

  Fly   376 ----------TKPWHRVIWSSSSAVGTSYRSLMGGAVQSGFRAAVNAVFVVRPQVVSWKDMLVEQ 430
                      |.|:.|:.::...   |:|..   |.|::..::|:.|...:..:.....|  ...
Human   482 ALWQTEKDDWTVPYGRIYFAGEH---TAYPH---GWVETAVKSALRAAIKINSRKGPASD--TAS 538

  Fly   431 PK-NGQDVVSAGRIRGLLS------------------RLNLYNVT 456
            |: :..|:...|.:.|:.|                  :|:|.|.|
Human   539 PEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTT 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shps	NP_651239.1	NADB_Rossmann	11..>53	CDD:304358	15/42 (36%)
		Amino_oxidase	21..409	CDD:279874	75/490 (15%)
IL4I1	NP_001244946.1	NAD_binding_8	86..143	CDD:290186	17/58 (29%)
		Amino_oxidase	91..523	CDD:279874	76/494 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1231
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740