Protein Alignment Orct and SV2B

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 109/559 - (19%)
• Similarity: 192/559 - (34%)
• Gaps: 184/559 - (32%)

  Fly   123 VCSRSLLSATSD------------SLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLA 175
            |.|.:|.||..|            .:..||::.|:.|.|.::||||||.....||.:...|..|:
Human   128 VVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLS 192

  Fly   176 AVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYR-----------LFAGV-AMQMFFSV 228
            :....|.::...|:|.|....|...:.:....|.:....|           :..|: |..|.:|:
Human   193 SFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSI 257

  Fly   229 ----GFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAK 289
                |:..:.|..|..|.||...|...||..:.:.....:|||.|:||..|:.|||::|:::...
Human   258 IPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHD 322

  Fly   290 EN--KVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFD---LLRYPNL--------------- 334
            .|  ....|.:::  .|..:...|:.||....|.:...:.   |:|:..:
Human   323 TNMRAKGTPEKVF--TVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGP 385

  Fly   335 -RRKTLLIFFDWFVNSGVYYGLS-W----------------------------NTNNLGGNQ--- 366
             |..||::...||..:..||||: |                            ..|....||
Human   386 YRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQ 450

  Fly   367 ----------------------------------------------------------------- 366
                                                                             
Human   451 HGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFI 515

  Fly   367 ------------------------LVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGIS 407
                                    ||:|:.|.:| :||..:....::|.||..::.|:|:::.:.
Human   516 NSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSV-LPGNIISALLMDRIGRLKMIGGSMLISAVC 579

  Fly   408 LLATIFVPSD---MNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGI 469
            .....|..|:   :.|..:.|.     ...:::..:.:.:.|.:||..|....|..:.:.:.|.|
Human   580 CFFLFFGNSESAMIGWQCLFCG-----TSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAI 639

  Fly   470 LAP--YLKLLGEIWRPLPLIICGALSLTAGLLSLLLPET 506
            |..  :...:| |.:.:|:::..|..:..||::|.||||
Human   640 LGNTIFASFVG-ITKVVPILLAAASLVGGGLIALRLPET 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	109/559 (19%)
		MFS	135..491	CDD:119392	95/518 (18%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	109/559 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940