Protein Alignment Orct and GIT1

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_010022.1
• Gene: GIT1 / 850462
• SGDID: S000000695
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 577
• Identity: 101/577 - (17%)
• Similarity: 172/577 - (29%)
• Gaps: 211/577 - (36%)

  Fly    73 NERCSYYDVDYTEEYLNGSIPRSSNETKT-------------CSSYVYDRSKYLNSAVTEWNLVC 124
            |.|...||.:           |.:..|:|             .|.:......|:|.:::..|.|.
Yeast    19 NPRIIKYDAE-----------RRATRTETSKKDKWKNIVTIIASGFALISDGYVNGSMSMLNKVF 72

  Fly   125 --------SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAA----- 176
                    ..|.:|....:..::|::.|....|..:|...||.....:..:.:|...|.|
Yeast    73 VMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGT 137

  Fly   177 -VAPEYFSYTISRMIVGATTSGVFLVAYVIA---------------LEMVGSSYRLFAGVAMQMF 225
             |...::..|:.|.:||......:..:.:.|               |.||.:....|.|....:.
Yeast   138 TVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATII 202

  Fly   226 FSVGFMLTAGFAYFIHDW-----------------RWL----------QIAITLPGLLFLCYYW- 262
            |.:.:.:.:|..:....|                 ||.          :|...:|..|.|.:||
Yeast   203 FLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFLALKFYWK 267

  Fly   263 -IIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVF 326
             ::.....|.:.                 :.|..||.|:...:.....|.:.|.:..::
Yeast   268 RLLGTCGTWFMY-----------------DFVTFPNGIFSSTIISSVIKDQNDLVKVAE------ 309

  Fly   327 DLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRW 391
                                          ||            ::.|.:.:.|..:..:..:|.
Yeast   310 ------------------------------WN------------LLLGVLAVLGVPIGAYLSDRI 332

  Fly   392 GRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIF------------- 443
            ||:.    |:|......:  ||      .||:.||......||..:...|.|
Yeast   333 GRKY----TLMFGFSGYI--IF------GLIIGCAYDQLKKITPLFIIFYAFMNMLGNAGPGDML 385

  Fly   444 ---SAEQFPTVVRNVGLGASSMVARVGGILA-----PYLKLLGEIWRPLPLIICGAL-------- 492
               |:|...|.||.|..|.|::..::|.::.     |....||..|..:...|||.:
Yeast   386 GVISSEASATAVRGVFYGLSAVTGKIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGIIITYFF 450

  Fly   493 ---SLTAGLL-----------------SLLLPETLNKPMPETI---EDGENFGKKPA 526
               ||.:.|:                 .:...||..:.|..||   |:|.|..||.|
Yeast   451 VPHSLESDLMKQDVEFHNYLVSNGWTGKMGFDETDEESMVRTIEVEENGTNCSKKNA 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	93/560 (17%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	80/482 (17%)