DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and OCT2

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	129/549 - (23%)
Similarity:	235/549 - (42%)	Gaps:	90/549 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DDVI-THLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67
            ||.| :::|.||..|.....|:....:..|......||..::|.:.|.   ::.||...|  :.|
plant    21 DDTIESYIGSFGWAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWHCT---DSNSICHES--ISN 80

  Fly    68 LSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSAT 132
            :..                     :|:        :::.:|.|.:: |.::||.|.|:.|.:...
plant    81 ICI---------------------LPK--------TAWSWDYSPHV-SVISEWGLQCAGSFVKGL 115

  Fly   133 SDSLFMLGVLLGSLIFGQMSD-KLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTS 196
            .:|.|.:|.|:|.|:...::| .||||...|.|.::..|..:|...:|..:.|.:.|.:.|...:
plant   116 PESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVMAISTMLTVFSPNIWVYAVLRFVNGFGRA 180

  Fly   197 GVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIH--DWRWLQIAITLPGLLF-L 258
            .:...|.|::.|:||..:|...|:.....|.:||:.....||...  .||.|....::|.::: :
plant   181 TIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGFLSLPLMAYMNRGSSWRILYAWTSIPTIIYCV 245

  Fly   259 CYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVP-----NEIYEQLVDEVAEKKKQDEMAA 318
            ...:.:.||.|||.::||::||..|:::.|.....:|.     :..:..|..|..|:|....:
plant   246 LVRFFVCESPRWLFVRGRREEAISILKRVASIPSTDVSSGGAISMSFSSLPFEEDEEKPSTNV-- 308

  Fly   319 SQPAATVFDLLRYPNLRRKTLLIFFDW------------FVNSGVYYGLSWNTNNLGGNQLVNFM 371
                 .:|..::        :|:...|            |....||||:....:||..|..::..
plant   309 -----NIFTTMK--------VLVEKRWALKRLSAVMAIAFGIGLVYYGMPLALSNLDFNIYLSAA 360

  Fly   372 ISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDM-----NWLIVACAMIGKL 431
            .:..:::|...:.||.:::..||:.|.|...:.|:|.: .||...:|     ..|.:|..:|...
plant   361 FNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSV-LIFALHNMRIGNHGALQLALELISYF 424

  Fly   432 AITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGE---IWRPLPLIICGALS 493
            :..|::....|::.|.|||.|||..:..:.....:||:.:|.:...|.   .|.      .|...
plant   425 SACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSPIMVAAGRKNAFWS------FGLFG 483

  Fly   494 LTAGLLSLL---LPETLNKPMPETIEDGE 519
            |..|||.|.   ||||....:.:|:::.|
plant   484 LAIGLLGLFAVGLPETRGSDLCDTMDEEE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	124/534 (23%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	91/384 (24%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	107/469 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm8406
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010