Protein Alignment Orct and Slc22a23

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 616
• Identity: 144/616 - (23%)
• Similarity: 250/616 - (40%)
• Gaps: 124/616 - (20%)

  Fly     1 MGYD-DVITHLGEF-GPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRC-------------- 49
            :.|| .|:..||.. |.|||.:..|..:||:...|.:.:..|||.:|||.|
Mouse    78 LDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPDFWCRGAGKGTELAGATV 142

  Fly    50 --------------ALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETK 100
                          |.|:...|        |..:   :.|.:..|.....     |.|...|...
Mouse   143 TGRWGDMGNWTSPSATPFSTAS--------WGTT---SNRSNSSDTPPLP-----SPPGKGNNDS 191

  Fly   101 TCSSYVYD---RSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFF 162
            .|..:.:|   |:..:.:.|::|:|||..:.....:....::|::.|.||.|.::|.:||:|...
Mouse   192 NCDCHAWDYGIRTGLIQNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLL 256

  Fly   163 ASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFS 227
            .|.:..||||:..|::.....::..|...|...:|:.|..|.:.:|:.....|....:.......
Mouse   257 FSTIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAM 321

  Fly   228 VGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENK 292
            .|..|..|.|....||:.||..|..|.||.|.|:.|.|||.|||:...:.:.|..:|....::|.
Mouse   322 AGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNC 386

  Fly   293 VEVPNEI---YEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYG 354
            |...::|   ..:|..|::.:.|:         ..:..::...||.:..:::    .|||...||
Mouse   387 VSPESDIKGVMPELEKELSRRPKK---------VCIVKVVGTRNLWKNIVVL----CVNSLTGYG 438

  Fly   355 LSWNTNNLGGNQLVNFMISGAVEIP--------GYTL----------LLFTLNRWGRRSILCGTM 401
            :.        :.....|:...|::|        .||:          :...:...|||.   |.:
Mouse   439 IH--------HCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVKFLGRRG---GLL 492

  Fly   402 MVAGISLLATIFVPSDMNWL---------------------------IVACAMIGKLAITSSYGT 439
            :...::.||::.....:|.:                           .:|.:::|..| :.:.|:
Mouse   493 LFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFA-SHAVGS 556

  Fly   440 IYI-FSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLL 503
            :.: |.||..|||:|..|||.....|..|.:.||.::|..:....|..||....:|...:..|||
Mouse   557 LSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLL 621

  Fly   504 PETLNKPMPETIEDGENFGKKP-APQETAEE 533
            ||:.|:.:||.|.:||::.::| .|.:..|:
Mouse   622 PESRNQNLPENIANGEHYTRQPLLPHKKGEQ 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	133/583 (23%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		6/41 (15%)
		MFS_SLC22A23	187..608	CDD:341002	101/445 (23%)