DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Orct and LOC685081

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	537	Identity:	177/537 - (32%)
Similarity:	288/537 - (53%)	Gaps:	39/537 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67
            :..|:..:|:|||:|.|:..|:.:|..:.||...:.||::......|::.:       :..|.:|
  Rat     4 FAQVMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHCSVSW-------VKNHTFN 61

  Fly    68 LSYPEN-------------ERCSYYDVDYTEEYLNGSIPRSSNETKTCSS---YVYDRSKYLNSA 116
            ||..|.             |.|..:........|...:....|||:.|.|   |..:|...|.:
  Rat    62 LSAAEQLAVSIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYPENRPPSLKN- 125

  Fly   117 VTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEY 181
              |::|||.|..|..||.|:||.|:|:|:|:||.:.|.:||:.:....::|..|.||..|..|.:
  Rat   126 --EFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAFVPSF 188

  Fly   182 FSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWL 246
            ..|.:.........:|..:...::..|.||.|:|..|.|..|..|::|.|..||.||.:.:||.|
  Rat   189 ELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALGLMALAGLAYGVRNWRLL 253

  Fly   247 QIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKK 311
            ||..|.|..|.:.|:|::|||.||||.:||.:||..:::|||..|...:.:|:..|||.|
  Rat   254 QIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLVPE----- 313

  Fly   312 KQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAV 376
                  .:.|:....||.|:|.||:.||::...|||:|.:||||.:...:.|.:..:..:|.|.|
  Rat   314 ------KTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVV 372

  Fly   377 EIPGYTLLLFTLNRWGRR-SILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTI 440
            |:|.....:..:.:.||: |.|| |:.:||:..:..||:|.|:..:..|.|::||.|.::::...
  Rat   373 EVPARLSSIPMMEKLGRKWSQLC-TLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTIS 436

  Fly   441 YIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPE 505
            |:::||..||::|..|:|..|:.:|||||:.|.:.||.:..:.:|::|.|:|.:.||||..||||
  Rat   437 YVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPE 501

  Fly   506 TLNKPMPETIEDGENFG 522
            |..:.:.:|::|.|..|
  Rat   502 TRGQTLKDTLQDLEQGG 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	172/519 (33%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	124/356 (35%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	172/519 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm9087
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.950