Protein Alignment Orct and Slc22a23

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 142/594 - (23%)
• Similarity: 249/594 - (41%)
• Gaps: 97/594 - (16%)

  Fly     1 MGYD-DVITHLGEF-GPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELS- 62
            :.|| .|:..||.. |.|||.:..|..:||:...|.:.:..|||.:|:|.|   :..|...||:
  Rat    78 LDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWC---HGAGKGTELAG 139

  Fly    63 -------PHLWNLSYPENERCSYYDVDYTEEYLNG-------SIPRSSNETKTCSSYVYD---RS 110
                   ..:.|.:.|.....|......|....|.       |.|...|....|..:.:|   |:
  Rat   140 ATVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCECHAWDYGIRT 204

  Fly   111 KYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLA 175
            ..:.:.|::|:|||..:.....:....::|::.|.||.|.::|.:||:|....|::..||||:..
  Rat   205 GLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFILIFGLTV 269

  Fly   176 AVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFI 240
            |::.....::..|...|...:|:.|..|.:.:|:.....|....:........|..|..|.|...
  Rat   270 ALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALC 334

  Fly   241 HDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEI---YEQ 302
            .||:.||..|..|.||.|.|:.|.|||.|||:...:.:.|..:|....::|.|...::|   ..:
  Rat   335 RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPE 399

  Fly   303 LVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQL 367
            |..|::.:.|:         ..:..::...||.:..:::    .|||...||:.        :..
  Rat   400 LEKELSRRPKK---------VCIVKVVGTRNLWKNIVVL----CVNSLTGYGIH--------HCF 443

  Fly   368 VNFMISGAVEIP--------GYTL----------LLFTLNRWGRRSILCGTMMVAGISLLATIFV 414
            ...|:...|::|        .||:          :...:...|||.   |.::...::.||::..
  Rat   444 ARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVRFLGRRG---GLLLFMILTALASLLQ 505

  Fly   415 PSDMNWL---------------------------IVACAMIGKLAITSSYGTIYI-FSAEQFPTV 451
            ...:|.:                           .:|.:::|..| :.:.|::.: |.||..|||
  Rat   506 LGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFA-SHAVGSLSVFFCAEITPTV 569

  Fly   452 VRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIE 516
            :|..|||.....|..|.:.||.::|..:....|..||....:|...:..|||||:.::.:||.|.
  Rat   570 IRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIA 634

  Fly   517 DGENFGKKP 525
            :||::.::|
  Rat   635 NGEHYTRQP 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	133/570 (23%)
		MFS	135..491	CDD:119392	92/404 (23%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		4/25 (16%)
		MFS_SLC22A23	187..608	CDD:341002	101/445 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940