Protein Alignment Orct and Slc22a4

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 193/563 - (34%)
• Similarity: 297/563 - (52%)
• Gaps: 54/563 - (9%)

  Fly     3 YDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67
            ||:||..||::||:|:.|::||....|...|:.::.|||...|:.||.:|:    ...||....|
  Rat     4 YDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPH----TVNLSSAWRN 64

  Fly    68 LSYPEN--------ERCSYY-----------------DVDYTEEYLNGSIPRSSNETKTC-SSYV 106
            .|.|..        :.|..|                 |||.  |.|         |.::| ..:.
  Rat    65 HSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDL--EQL---------EQESCLDGWE 118

  Fly   107 YDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIF 171
            |.:..:|::.||||||||.....:..:.|||.:|||.||.:.||:||:.|||...||::.:|..|
  Rat   119 YSKDVFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGF 183

  Fly   172 GVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYR-LFAGVAMQMFFSVGFMLTAG 235
            ..:...:..:..:|:...|||......::||:::..|::..|.| ||:.:.:..||::|:|:...
  Rat   184 SFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPL 248

  Fly   236 FAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIY 300
            |||||.|||.|.:|:|||||..:..:|.||||.|||:.:.|.:||..||:||||.|.:..|..|:
  Rat   249 FAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIF 313

  Fly   301 EQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGN 365
            :.|       :.|:..:..|....:.||.:..|:...|::....|.:.|..|:.||.|..||.|:
  Rat   314 DPL-------ELQELNSLKQQKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGD 371

  Fly   366 QLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGK 430
            ..:|..:||.:|:|.|......|....||.|:.|.:...|..||....||.|.|::.:...|:||
  Rat   372 VYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYNFVSIGLVMLGK 436

  Fly   431 LAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLT 495
            ..:||::..:|:|:||.:||:|||:.:|.:||.:|||.|:|||...||...|.||.|:.|:|::.
  Rat   437 FGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVL 501

  Fly   496 AGLLSLLLPETLNKPMPETIED-----GENFGKKPAPQETAEE 533
            .|:::|..||:....:||.:|.     |...|||.......||
  Rat   502 IGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTVSMDREE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	180/529 (34%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	179/528 (34%)