Protein Alignment Orct and Slc22a17

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.1
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 520
• Species: Mus musculus
• Alignment Length: 516
• Identity: 147/516 - (28%)
• Similarity: 235/516 - (45%)
• Gaps: 44/516 - (8%)

  Fly    39 VFLLAKPDFRC---ALPYENGSIYELSPHLWNLSYPENERCSYYD---VDYTEEYLNGSIPRSSN 97
            :|.|| |...|   ||| .|.|.:|..|:...:|.......:...   |..|:...:|..|...|
Mouse     6 IFTLA-PPLHCHYGALP-PNASGWEQPPNSSGVSVAGAALAASAASGVVTSTDPSCSGFAPPDFN 68

  Fly    98 ETKTC-SSYVYDRSKYL-NSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPT 160
            .   | ..:.|:....| .:|:.:|:|||...........||:||...|.|..|..:|:.||:..
Mouse    69 H---CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGI 130

  Fly   161 FFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMF 225
            ...:|.|....||..|.|.........|.::|...:||.|..|::.||:...:.||...:|.::.
Mouse   131 VLLTLGLVGPCGVGGAAAGSSTGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELV 195

  Fly   226 FSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYW--IIPESARWLLMKGRKDEAFVIIEKAA 288
            ...|..|..|.|....|||:||..||.|.:|||.|.|  :..||||||::|.:.:||..::...|
Mouse   196 GVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILA 260

  Fly   289 KENKVEVPNEIYEQLVDEVAEKKKQD-EMAASQPAATVF---DLLRYPNLRRKTLLIFFDWFVNS 349
            :.|:.      :.|::.|.|::..|: |.....||.:.|   .||.|.|:.:..|::.|..|:..
Mouse   261 ERNRP------HGQMLGEEAQEALQELENTCPLPATSTFSFASLLNYRNIWKNLLILGFTNFIAH 319

  Fly   350 GVYYGLSWNTNNLGGN----QLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLA 410
            .:.:  .:.....||:    .|.:.:.||...: ....|..|::|:|||.||..:|.:.||:.|.
Mouse   320 AIRH--CYQPVGGGGSPSDFYLCSLLASGTAAL-ACVFLGVTVDRFGRRGILLLSMTLTGIASLV 381

  Fly   411 TIFVPSDMN-WLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYL 474
            .:.:...:| ..|...:::|..:..:|.....:.::|..||.||..|||....:..:||:..|..
Mouse   382 LLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALGALGGLSCPAQ 446

  Fly   475 KL---LGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE-----NFGKKPAP 527
            :|   .|...:.:.|..|..|.:   |..:|||||..|.:||.:.|||     :..::|.|
Mouse   447 RLHMGHGAFLQHVVLAACALLCI---LSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	141/496 (28%)
		MFS	135..491	CDD:119392	106/369 (29%)
Slc22a17	NP_001347335.1	MFS_SLC22A17	63..476	CDD:341003	119/427 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843374
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940