DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG4459

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	586	Identity:	129/586 - (22%)
Similarity:	224/586 - (38%)	Gaps:	120/586 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DVITHL-GEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNL 68
            ||:..: |.||.:|.|...|:.|..|..|:  ...:.:...|     .|::...:  ..|..||:
  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAW--FTAIIIYTAP-----YPWKGELV--CHPADWNV 74

  Fly    69 SYPENERCS--------------YYDVDYTEEYLN----GSIPRSSNETKTCSS----------- 104
            |..:.|...              .::||....|.|    |.:.....|.....|
  Fly    75 SRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPC 139

  Fly   105 -YVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQ 168
             :|..|:.| .|.:::::|:|||.:|.|.:.|...||.|:|.|:......|:..:......::.|
  Fly   140 EHVEHRTDY-KSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQ 203

  Fly   169 LIFGVLAAVAPEYFSYTISRMIVG-----ATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSV 228
            :..|.|..:...|..:...|.:..     ..|||.|::.     ::.....|:......::|:|:
  Fly   204 IFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILN-----DITSGKARIIVVTLSELFWSM 263

  Fly   229 GFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKV 293
            |.:|....:.:..:|.:|.:||:...::.:..:..|.::.||||...|.:.|...:.::|..|..
  Fly   264 GLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNR 328

  Fly   294 EVPNEIYEQL---VDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGL 355
            :||..:..||   .:::.:|.||     ......|:|    ...:|..|           ||..|
  Fly   329 KVPLTLDVQLTMYANDLDQKSKQ-----KHSYCQVWD----GETKRSQL-----------VYIHL 373

  Fly   356 SWN------------TNNLGGNQL-VNFMISGAVEI----PGYTLLLFTLNRWGRRSILCGTMMV 403
            .|.            ..|||..|: ||....|..|:    .|..|:|:|...|.....|   |::
  Fly   374 IWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNL---MII 435

  Fly   404 AGISLLATIFVP-SDMN----------WLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGL 457
            ||:|......:| ::.|          |||:..|....:|:.::. |..|.|.|:...::.:|
  Fly   436 AGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTC-TSEIVSKEKRVVLMLSV-- 497

  Fly   458 GASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLL---------PETLNKPMPE 513
               ...:||..:..|:|..|..|...:|:.|...:....||....|         |:....|.|.
  Fly   498 ---ISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPN 559

  Fly   514 T 514
            |
  Fly   560 T 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	126/577 (22%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	87/391 (22%)
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	121/553 (22%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	91/409 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450234
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950