DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG4465

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	582	Identity:	144/582 - (24%)
Similarity:	222/582 - (38%)	Gaps:	135/582 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DDVITH-LGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67
            |||||| :|.|||:|.|...:|.|..|..|:  .....|...||.
  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIPAAW--FMACILFTAPDL-------------------- 101

  Fly    68 LSYPENE-RCSYY----DVDYTEE----YLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLV 123
              |||.| :|...    ||:.|..    |:..:...|:...:.|..::|...  .:|...|::||
  Fly   102 --YPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTG--FHSLTMEFDLV 162

  Fly   124 CSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGR--------KPTFFASLVLQLIFGV------- 173
            |......|.|....:.|:|:|    |..:.||.|        :...:..|:..|:.|:
  Fly   163 CLCDFFVAWSQYWHLFGLLIG----GVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLH 223

  Fly   174 -----LAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLT 233
                 ||||:. .|..|..:.|.|..|:|               .||:...:....|:::|.:|.
  Fly   224 CGLRCLAAVSC-CFMITSGQYIFGDITAG---------------KYRVGTLILYDCFWALGLILL 272

  Fly   234 AGFAYFIHDWRWLQIAITLPGLLFLCYY--WIIPESARWLLMKGRKDEAFVIIEK-------AAK 289
            .|.|.....|:.:.:.:|| .||.:.:.  | .|:|.||.|...:  ||.:.||:       ||:
  Fly   273 PGLASNAPSWQHIYLGVTL-SLLVIVFLLPW-TPDSPRWQLQHTK--EAQLAIERTVGILLEAAR 333

  Fly   290 EN--KVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKT---------LLIFF 343
            .|  ..:|..|:.:|| :|:.|:     |....||.....|  :...||.|         |..|.
  Fly   334 TNGRMHKVSKELPQQL-EELRER-----MLEPMPAVHWMHL--WMGQRRSTFHLVAVHMALATFM 390

  Fly   344 DWFVNSGVYYGLSWNTNNLGGNQLV-NFMISGAVEIPGYTLLL-FTLNRWGRRSILCG--TMMVA 404
              .||:    ||..:..:.|...|| |.:..|..|:.|..|.| .|.|...|:....|  .::|.
  Fly   391 --VVNT----GLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVG 449

  Fly   405 GISLLATIFVPSDMN-----WLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMV- 463
            .|..:.......||.     .|.:..|.:.:.|:..:...|.....|..|...|:. |..|::.
  Fly   450 CIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSC-LSFSAVTW 513

  Fly   464 ARVGGILAPYLKLLGEIWRPLP------LIICGALSLTAGLLSLLLPETLNKPMPETIEDGE 519
            |||..:.|.:|.||.::...|.      |:|.|.|    |...|:..:....|:...:..|:
  Fly   514 ARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL----GTCCLVTRDKEQPPVGAVVNKGQ 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	137/567 (24%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	100/411 (24%)
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	135/554 (24%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	35/155 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450233
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950