DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG17751

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	155/577 - (26%)
Similarity:	254/577 - (44%)	Gaps:	82/577 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALP--YENGSIYELSP 63
            |....|:...|.|||||..:..|.....||.:.|..:...:...|..||:.|  |:..|...||
  Fly     1 MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTPSHRCSRPEDYQPNSTSLLS- 64

  Fly    64 HLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSL 128
                        ||....|  :|:             .|:|:.::|.....|..||...||..:.
  Fly    65 ------------CSVMQFD--KEF-------------KCTSWDFERESNYESITTELEWVCDDAY 102

  Fly   129 LSATSDSLFMLGVLLGSLIFGQMSDKLGRKPT------------FFASLVLQLIFGVLAAVAPEY 181
            ..|...|.|.:|..|||:.||.::|::||.|.            ||.|.|..|          .:
  Fly   103 KLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSL----------PW 157

  Fly   182 FSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFA-GVAMQMFFSVGFMLTAGFAYFIHDWRW 245
            ||:|  |.|.|......:::.|::..|.:...:|.|. .:.:.:|:.||.|::...|.::.:||.
  Fly   158 FSFT--RFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRN 220

  Fly   246 LQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEK 310
            ...|.:||.|..|.:...:.|||.|||.||:.::|...:...||.|..:|.:.::::.:....||
  Fly   221 YLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREK 285

  Fly   311 KKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGA 375
            ....:..:|.   |...:||.|.||:.|:::.....:.:..:..||.|...:|.:....|..||.
  Fly   286 LNNSQNKSSD---TFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGF 347

  Fly   376 VEIP-GYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFV-----PSDMNWLIVACAMIGKLAIT 434
            ..:| |.|::||. |:.||:.:.|.::.|..|...||.::     |||.:.|:.....:|:....
  Fly   348 CYLPAGLTIILFQ-NKIGRKGMACASLFVGAIITAATGYLVATLDPSDYSVLLGFMVSLGRYGAV 411

  Fly   435 SSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLL 499
            .:|.....::||..||.|:..|:....:|.......:.|:..||..::|||.::...:.|....|
  Fly   412 VAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACL 476

  Fly   500 SLLLPETLNKPMPETIEDGENFGK-----------------KPAPQETAEEGGTQEL 539
            .|.|||||:|.:|:.:|:||.|.|                 |.|.|..:.:|.|.:|
  Fly   477 CLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNKL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	142/523 (27%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	101/374 (27%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	141/522 (27%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	104/387 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	3.940