DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG6006

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	173/554 - (31%)
Similarity:	275/554 - (49%)	Gaps:	65/554 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DVITHL-GEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLW-N 67
            |||..| |.:|.:|..:..||.|..:...||..:.::..|..||.|..|   ..:..:....| |
  Fly    83 DVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRP---AQLQHMPVATWRN 144

  Fly    68 LSYPENERCSYYDVDYTEEYLNGSIPRSSNET------KT----------CSSYVYDRSKYL-NS 115
            ||...:....:..:|:::         .||||      ||          |..:.|:.:..: |:
  Fly   145 LSGSVDNCRRWEGIDWSQ---------VSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVGNT 200

  Fly   116 AVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPE 180
            ..::|:|||.:..|...::..|:|||..|.:|.|.:|||.|||...|.|.|||.|||:...:...
  Fly   201 WTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSS 265

  Fly   181 YFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRW 245
            :..|...|.::|..:..|.....::|:|.|...:|..||:.......:.:|:.:|.||...|::.
  Fly   266 FELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLAYLTQDYQR 330

  Fly   246 LQIAITLPGLLFLCYYW-IIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAE 309
            ||:.|.:|| :|||:.| ::|||.||||:|||.||...|||.|||.|..::|.:.  ||.....|
  Fly   331 LQLCIGIPG-IFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQLPADY--QLTPPTQE 392

  Fly   310 KKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISG 374
            ...||          |..|.|...|||.::..|..||..:.||||:..|.::.|||..:|..::|
  Fly   393 SSTQD----------VTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAG 447

  Fly   375 AVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVP--SDMNWLIVACAMIGKLAITSSY 437
            .||||...:.::.:.:.|::.:.|.|::.||::........  :|:.||.:...|:||..|::..
  Fly   448 LVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADLLWLKITFLMMGKFTISAGN 512

  Fly   438 GTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLL 502
            ..:.:::||.:||.:||||:||.::.|.:..||.|||.||.:|...|.:.:..|.|:..|.:.|.
  Fly   513 TIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAWSIFGGFVVLF 577

  Fly   503 LPETLNKPMPETIEDGENFGKKPAPQETAEEGGT 536
            ||||..:                  |:|..:||:
  Fly   578 LPETAVR------------------QKTDNQGGS 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	165/523 (32%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	125/358 (35%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	163/515 (32%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	129/369 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13331at6656
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.070