DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG44098

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001262264.1	Gene:	CG44098 / 40590	FlyBaseID:	FBgn0264907	Length:	813	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	131/573 - (22%)
Similarity:	243/573 - (42%)	Gaps:	73/573 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKP---DFRCALPYENGSIYELSPHLW-NLSYP 71
            |.:|.:|.|...|:.|..|..::.....:|....|   :|.|..|:..|:..:..   | .:|:|
  Fly   214 GPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRHGEFFCKPPHTIGAQNQTQ---WIKVSHP 275

  Fly    72 ENER----------CSYYD--VDYTEEYLN------------GSIPRSSNETKTCSSYVYDRSKY 112
            :.|.          |:.|.  .::...|.|            ..:.|:|| ...|:.:.:: |.|
  Fly   276 QKEESDDQEFSIDFCNVYQDAQEHAHHYYNYENSDQEPRVWEKPLHRNSN-VIPCTEFQHE-SDY 338

  Fly   113 LNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAV 177
             :|.||:::|||||.:|.:.:....:.|||.|.::..|:......:......::.|:..|.|...
  Fly   339 -HSVVTQYDLVCSRDILVSVTQFFHLFGVLTGGILANQLLKYFSPRNVMLFGMITQIFCGNLTGH 402

  Fly   178 APEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHD 242
            ...|..:...|.:.....:.::.....|..::.|..||.......:.|:|:|.|:..|.|.|...
  Fly   403 VASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVSTLFEQFWSIGVMMLPGVASFWSS 467

  Fly   243 WRWLQIAITLPGLLFLCYYW-IIPESARWLLMKGRKDEAFVIIEKAAKENKV--EVPNEIYEQLV 304
            |..|.:||:.|.:: |.|.| .||:|.|||:.:||..:|..|:.:..:.|..  .:|::|.:||
  Fly   468 WSHLYMAISWPTVI-LIYLWQWIPDSPRWLIARGRTQDAKKILLECVEVNGTGYNLPHDIDQQL- 530

  Fly   305 DEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQL-V 368
                |.:.|..|.|..|:.. :.:.:.....|..:.:...|.:...||||:..|..:...:.| :
  Fly   531 ----ELQAQTAMDAPPPSGW-WSMWKGERAVRHIVCVHLAWSLYIVVYYGMLLNIRSFSRDHLYI 590

  Fly   369 NFMISGAVEIP----GYTLLLFTLNRW---GRRSILCGTMMVAGISLLATIFVPSDMNWLIVAC- 425
            |...:|..|:.    |..|:|.|..:|   |..:|:.|.:...|..:.....:..|.|..::.|
  Fly   591 NTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAYCGWLVPKPSVIGLDPNVALLMCS 655

  Fly   426 AMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYL---KLLGEIWRPLPLI 487
            ||:.|:||:::...:...:.|......:.:...::...||...:.||::   .:.|::   :|..
  Fly   656 AMVSKMAISTTLSILTTCTVELVSDDKKKITSFSTICWARFWLLGAPFIGSTVVFGQL---IPQT 717

  Fly   488 ICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEEGGTQELS 540
            ...:|::..||.:.|:......|:...        ..||.|      |||.::
  Fly   718 AFASLAILGGLCTSLISSPRTHPISRP--------SSPAAQ------GTQNIT 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	125/545 (23%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	84/370 (23%)
CG44098	NP_001262264.1	2A0119	214..730	CDD:273328	123/531 (23%)
CG44098	NP_001262264.1	MFS	353..733	CDD:119392	88/389 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950