Protein Alignment Orct and slc22a6l

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_996960.2
• Gene: slc22a6l / 404609
• ZFINID: ZDB-GENE-040426-2249
• Length: 560
• Species: Danio rerio
• Alignment Length: 556
• Identity: 164/556 - (29%)
• Similarity: 285/556 - (51%)
• Gaps: 59/556 - (10%)

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHL 65
            |.:.|::..:|..|.:|.....||.:|.::.|.|.|...|:.|.|...|            .||.
Zfish     1 MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHC------------QPHA 53

  Fly    66 WNLSYPEN------------------ERCSYY--------DVDYTEEYLNGSIPRSSNETKTC-S 103
             |||....                  |||..|        .::.:|...:.|:  :..||::| .
Zfish    54 -NLSMSSTDAMDVLRATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESM--AETETQSCED 115

  Fly   104 SYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQ 168
            .:.|:.::..::.:|||:|||....|...|.:.:|.|||:|:::||.:||:.||:.....|.::.
Zfish   116 GWFYNMTEMSSTIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMM 180

  Fly   169 LIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLT 233
            .|.|...|.:..:..:.:.|:..|...||:.|.::.:.:|.:.:..|...|......::.|.::.
Zfish   181 AIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTGTGYCYTTGQLIL 245

  Fly   234 AGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKEN------- 291
            |..||.|.|||||.:|::||..:...|.|...||||||::..:.::|...::..|:.|
Zfish   246 AAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGD 310

  Fly   292 KVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLS 356
            |:::          |:.::..:.|||.|:.:.:..||||...:|..|:.:...||..|..|||||
Zfish   311 KIDL----------EMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLS 365

  Fly   357 WNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWL 421
            .:....|.:..:..:|.|||:||...::...::..|||...||.:::|||.:|..:.||||:..|
Zfish   366 MDLQKFGVSIYLIQIIFGAVDIPAKIIVTICMSMLGRRPSQCGALVLAGIMILINLLVPSDLQML 430

  Fly   422 IVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPL 486
            ..:.|:|||..:.:|:...|:::.|.:|||:|..|:|..||:||.|.::||.:.|||:.:..:|.
Zfish   431 RTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPG 495

  Fly   487 IICGALSLTAGLLSLLLPETLNKPMPETIEDGENFG 522
            .|.|...:.:|:.:..|||||::|:|:||:|.::.|
Zfish   496 FIYGGAPIVSGIFAFFLPETLSQPLPDTIQDIDDRG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	158/536 (29%)
		MFS	135..491	CDD:119392	113/362 (31%)
slc22a6l	NP_996960.2	2A0119	11..523	CDD:273328	158/536 (29%)
		MFS	116..513	CDD:119392	124/406 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588747
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.980