Protein Alignment Orct and SLC22A

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 177/548 - (32%)
• Similarity: 286/548 - (52%)
• Gaps: 52/548 - (9%)

  Fly     4 DDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCA-----LPYENGSIYELSP 63
            |.::.|||:||.:|..|:.|:|||.:..|...:..||..|....||:     ||..|  .||  |
  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSN--YYE--P 88

  Fly    64 HLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSK---------YLNSAVT- 118
            |. |.|.|:|.:    |:|....|.|..:|:.::....||:..:.::|         :.:..||
  Fly    89 HT-NWSIPKNGK----DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTI 148

  Fly   119 ----------EWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGV 173
                      ||.|    |::...::    ||...|..|.|.::|:.||..:.....:|..:.||
  Fly   149 SNDFGIFCDDEWKL----SMVGTINN----LGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGV 205

  Fly   174 LAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAY 238
            :.:.:|.|..:.:...:...|:|.::...:||.:|:||...|:.|...:.:|::||.:|.|..|.
  Fly   206 IRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAK 270

  Fly   239 FIHDWRWLQIAITL-PGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQ 302
            ..||||.| :.||. |.|:.|.|:||:|||.||||.:|:::.|..|:.:||..||.|:|..:.::
  Fly   271 AFHDWRIL-LRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDK 334

  Fly   303 LVDEVAEKKKQDEMAASQ-PAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQ 366
            ||  :|.:.|..:.:.|: |....|     .|.:.:.......|.|:..||||||.|...|.|::
  Fly   335 LV--LANRDKLQQSSESRFPIREAF-----KNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDK 392

  Fly   367 LVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKL 431
            ..||.....|||||:.:.|..::|:|||..|||.|:.:|:..:.|||..:|...|.:...::|||
  Fly   393 YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKL 457

  Fly   432 AITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTA 496
            .||:|:..:|.|::|.:||.:||..|...||:.|.|.:|||...||.:.:...|.::....::.:
  Fly   458 TITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVS 522

  Fly   497 GLLSLLLPETLNKPMPETIEDGENFGKK 524
            |||:|..|||.|..:|.|:::.:..|.|
  Fly   523 GLLTLFFPETTNVVLPTTVQEADAIGVK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	171/529 (32%)
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	132/409 (32%)