Protein Alignment Orct and Slc22a14

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 550
• Identity: 151/550 - (27%)
• Similarity: 256/550 - (46%)
• Gaps: 40/550 - (7%)

  Fly     3 YDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGS-IYELSPHL- 65
            :..|:..:||||.:|.|:..|..:|:|:..|...:..|||.     ...||.|.| |.|:.|:|
Mouse    51 FASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLT-----AQRPYCNTSWILEVGPNLT 110

  Fly    66 ----WNLSYPENERCS------YYDVDYTEEYLNGSIPRSSNETKTCS-SYVYDRSKYLNSAVTE 119
                .||:.|.....|      |..|.:.   |:..|....|.|:||. .::|..: :..|.:.|
Mouse   111 EDEQLNLTLPRAPNGSFLTCLMYIPVPWD---LDSIIHFGLNYTETCKFGWIYPFA-HTRSLINE 171

  Fly   120 WNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSY 184
            ::|||..........::|:.|||.|||:||.:||||||.|....||:..||||...|....::.|
Mouse   172 FDLVCGNEPNKENGLTVFLSGVLTGSLLFGFLSDKLGRYPIILLSLLGFLIFGFGTAFVSSFYQY 236

  Fly   185 TISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIA 249
            ...|..|...:.|..:.:..:.:|.:...:|..|.:....|.::|.:|..|.||.:..||.|.:.
Mouse   237 LFFRFFVAQASVGYAICSVSLVMEWLVGEHRAQAVILQHSFLTIGVILLTGLAYKVVHWRLLCLL 301

  Fly   250 ITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQD 314
            ..:|....:|..|::.||.|||:::|:.:||..::..||:.||..:|..:..:|  :::.||
Mouse   302 GGMPMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIPLNLLNEL--QISGKK--- 361

  Fly   315 EMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIP 379
                 ...|::.|.....:|.:..|.|...||..|.:.:.|:...|:.|.:.....|:...|.:|
Mouse   362 -----VAKASILDFCTNQHLFKVVLAIGCVWFTVSYISFTLNLKMNDFGLDVYFVQMVRSIVAVP 421

  Fly   380 GYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFS 444
            .....:..|..:||:..|..|:.:.....|..:|:|.:....|:...|:.:.::..:....:|::
Mouse   422 ARLCCIILLEYFGRKWALNLTLFLVTSMCLFLLFLPQEPKSTIILTLMLAEFSMAGTLSIFFIYT 486

  Fly   445 AEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNK 509
            ||..|||:|:.|||..|:....|.|.:  :.:..:....||:..|....:.|...|.|:|||.::
Mouse   487 AELLPTVLRSTGLGMVSLAWVAGAISS--VAIFKQTKTQLPIFFCCLCCVLALCFSSLVPETGSQ 549

  Fly   510 PMPETIEDGENFGKKP------APQETAEE 533
            .:.::||.......:|      .|...|||
Mouse   550 SLRDSIEYNIRDSIEPKDRNKDVPMVIAEE 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	143/515 (28%)
Slc22a14	NP_001032838.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		2A0119	59..553	CDD:273328	143/514 (28%)