Protein Alignment Orct and Slc22a20

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 553
• Identity: 182/553 - (32%)
• Similarity: 289/553 - (52%)
• Gaps: 20/553 - (3%)

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHL 65
            |.:.|::..||..|.:|.....||.||..:.|.|.....|..|.|...|..|............:
Mouse     1 MAFTDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEPTTNVSGV 65

  Fly    66 W-NLSYPEN-----ERCSYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLNSAVTEWNLV 123
            | ..:.|.|     |.|..| |:.....|..:.......|:.| ..:|||||.:.::.|.||:||
Mouse    66 WLRAAIPLNQHGDPEPCRRY-VEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEWDLV 129

  Fly   124 CSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISR 188
            |....|...:.|::|.|||:|:.:||.::|:||||.....|.:...:.|...|....:.:|.:.|
Mouse   130 CEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYCVFR 194

  Fly   189 MIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLP 253
            .::|.|.||:.|.:..:.:|.:.:..|..||:.:...|::|.::.||.||.|..|||||.|::.|
Mouse   195 FLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAP 259

  Fly   254 GLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKEN--KVEVPNEIYEQLVDEVAEKKKQDEM 316
            .|:|..|.|.:|||:||||:.|:..:|...::|.|..|  |.|     .|:|..||.....|||.
Mouse   260 FLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAE-----GERLTTEVVSSYIQDEF 319

  Fly   317 AASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGY 381
            |:.:.:.::.||.|.|.:||.|..:...||.||..||||:.:....|.:..:...:.|.::||..
Mouse   320 ASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAM 384

  Fly   382 TLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAE 446
            .:...|:...|||:.:...:::||:.::|.:|:|.|:..|....|.:||..:.||:..:|:|:.|
Mouse   385 LVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTGE 449

  Fly   447 QFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGL-LSLLLPETLNKP 510
            .:||.:|.:|:|.:|:.||:||::||.:..||||...||.:..||.|:.||: ::..|.||.|.|
Mouse   450 LYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAVACFLTETRNVP 514

  Fly   511 MPETIEDGENFGK----KPAPQETAEEGGTQEL 539
            :.|||...|...|    |...::.:||...|:|
Mouse   515 LVETIAAMERRVKQGRSKRDTEQKSEEISLQQL 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	169/512 (33%)
		MFS	135..491	CDD:119392	123/357 (34%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	169/512 (33%)
		MFS	138..507	CDD:119392	128/373 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		6/22 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.980