DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and CG4630

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001260948.1	Gene:	CG4630 / 36458	FlyBaseID:	FBgn0033809	Length:	582	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	202/596 - (33%)
Similarity:	318/596 - (53%)	Gaps:	99/596 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALP------------- 52
            :.:||::..:||||.:|:|.|.|:|||.:..|.:.|:.||....|.:||.:|
  Fly    13 LDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGAN 77

  Fly    53 ------------------------YENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIP 93
                                    ..||...|.|...|: ::|       .|..:.|.:
  Fly    78 WVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWS-AWP-------LDQCFAENF------ 128

  Fly    94 RSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLS-ATSDSLFMLGVLLGSLIFGQMSDKLGR 157
              :.||:.|:.:||..|:  .:.|.:|.|.|..:|.. |...::...|:::|:.:.|.::|:.||
  Fly   129 --TTETERCNQFVYGSSE--RTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGR 189

  Fly   158 KPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAM 222
            |..|...:|...:.||..|::.:|.|:....::....||||:.:|::|.:||||...|..:.:.:
  Fly   190 KHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVL 254

  Fly   223 QMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKA 287
            ..|::||..| .|.:.|:.|||.||:|:::|.|:.:.|:|::|||.||||.:.|:::|.|||.:|
  Fly   255 NYFYAVGEAL-LGLSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRA 318

  Fly   288 AKENKVEVPNEI-----YEQLVDEVAEK---------KKQDE--MAASQPAATVFDLLRYPNLRR 336
            ||.|:.::..|:     .::|..|..::         ||.|:  :|..:.|.:...:.||..|
  Fly   319 AKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAIL-- 381

  Fly   337 KTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTM 401
              |||   |.||:.||||||.|..:|.||:.:||.:...||||||:|....|.|:|||..|.|::
  Fly   382 --LLI---WAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSL 441

  Fly   402 MVAGISLLATIFVP-------------------SDMNWLIVACAMIGKLAITSSYGTIYIFSAEQ 447
            ::..|:.:|:.||.                   |..|||:|...::|||.||||:..||.|:||.
  Fly   442 LLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEM 506

  Fly   448 FPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMP 512
            .|||:|:.|:|..|..||.|.:|||::.||...:.||||::.|.|||.|||||||||||.|:.:|
  Fly   507 MPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLP 571

  Fly   513 ETIEDGENFGK 523
            :|:|:....||
  Fly   572 DTVEEAIALGK 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	196/575 (34%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	140/390 (36%)
CG4630	NP_001260948.1	2A0119	23..573	CDD:273328	196/575 (34%)
CG4630	NP_001260948.1	MFS	158..533	CDD:119392	136/382 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458341
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	9	8.900