DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Orct and SPBC8E4.01c

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_596846.2	Gene:	SPBC8E4.01c / 2541258	PomBaseID:	SPBC8E4.01c	Length:	572	Species:	Schizosaccharomyces pombe

Alignment Length:	483	Identity:	123/483 - (25%)
Similarity:	194/483 - (40%)	Gaps:	129/483 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 RSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMI 190
            |.|::|:::    :|.:.|.|:||.|.|..|||..:...:|:.:|..||....|:.....:|:|:
pombe    95 RGLVNASAN----IGNIFGQLLFGFMGDFFGRKFVYGKEMVIVIIATVLVIAMPKSIHSPLSKMM 155

  Fly   191 VGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQ-------------MFFSVGFMLTAG------- 235
                  .||...:::.:. :|..|.:.|.:..:             :|...||...||
pombe   156 ------WVFCWRWLLGVG-IGGDYPMSAAITSERSKIKRRGTLISLIFAFQGFGTLAGAIVTIIL 213

  Fly   236 FAYFIHD-------------WRWLQIAITL-PGLLFLCYYWIIPESARWLLMK------GRKDEA 280
            ...|.|.             || ||..:.| |.:..|....|:.||..:...|      |:..:|
pombe   214 LGCFEHPLNREGHYHKLEGVWR-LQFGLALVPAIGVLIPRLIMKESKSYENSKALNSAEGKDPKA 277

  Fly   281 FV------IIEKAAKENKVEV--PNEIYEQLVD----EVAEKKKQDEMAA------SQPAATVFD 327
            |.      .::|::.....||  .::.|....|    ||...:||  .||      |....|.|.
pombe   278 FFNTDDEDNMKKSSSHGDSEVVEASDRYANQADAADAEVDNIEKQ--FAAVTTPENSSGFITYFR 340

  Fly   328 LLRYPNLRRKTLL-IFFDWFVNSGVYYGLSWNTN----NLG------------GNQLVNFMISGA 375
            ..|:    .|.|| ....||:....:||::.|.:    |:|            .|.:.|.:|:.|
pombe   341 QWRH----FKHLLGTSVCWFLLDIAFYGVNLNQSVILKNIGFSTGTNEYRTLMKNAIGNLIIAVA 401

  Fly   376 VEIPGYTLLLFTLNRWGRRSILCGTMMVAGI--SLLATIFVPSDMNWLIV------ACAMIGKLA 432
            ..:|||...:|.:...||:.|.....::.|:  ::||.       .|..:      ||.:|.:|
pombe   402 GYVPGYWFNVFLVEILGRKWIQLQGFVITGLMFAILAG-------RWNEISTGGRFACFVIAQL- 458

  Fly   433 ITSSYG---TIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYL--KLLGEI------WRPLPL 486
             .|::|   |.:|:.||.||..||....|.|:.:.:.|.|||..|  .|.|.|      |
pombe   459 -FSNFGPNSTTFIYPAEVFPARVRGTAHGVSAALGKCGAILASLLFNFLTGVIGYGNVMW----- 517

  Fly   487 IICGALSLTAGLL-SLLLPETLNKPMPE 513
            |.||.  :..|:| :||||||..:...|
pombe   518 IFCGC--MWGGILFTLLLPETKGRDADE 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	123/483 (25%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	110/449 (24%)
SPBC8E4.01c	NP_596846.2	2A0109	27..547	CDD:129965	123/483 (25%)
SPBC8E4.01c	NP_596846.2	MFS	48..534	CDD:119392	118/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
TreeFam	0	0.000	Not matched by this tool.
	2	2.030