Protein Alignment Orct and Slc22a22

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 599
• Identity: 154/599 - (25%)
• Similarity: 266/599 - (44%)
• Gaps: 80/599 - (13%)

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELS--- 62
            |.:|:::.|:|:.|.:|..:..||.:.::|.:.|.:...|..|.|...|::..:| |..|:|
Mouse     1 MDFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDN-SRSEVSTDM 64

  Fly    63 ----PHLWNLSYP-----ENERCSYYDVDYTE-EYLNGSIPRSSN---ETKTC-SSYVYDRSKYL 113
                ..|..:|.|     :.|:|..:  .||: ::|:.:|...::   ||:.| ..:.||.|.:.
Mouse    65 NLTTEDLMKVSIPMGPNQKPEQCRRF--RYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVFT 127

  Fly   114 NSAVTE---------------------------------WNLVCSRSLLSATSDSLFMLGVLLGS 145
            ::.|||                                 |:|||........:.:..:.|.|:..
Mouse   128 STIVTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLVSC 192

  Fly   146 LIFGQMSDKLGRKP-TFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEM 209
            .:.|.:||:.|||| ..:.||....: |...|.||.:..|.:.|.::.|..|.:.:.:.::.||.
Mouse   193 PLSGIISDRFGRKPLLMYCSLAYGAV-GTYCAFAPNFSVYCVLRFLLSAFQSTILINSLILVLEE 256

  Fly   210 VGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMK 274
            ....:.....|...:|.|:|..:..|.||.|.||..||:|..||..:|...:..:|||.|||::.
Mouse   257 ASVQWHPTIIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCWVPESVRWLIIT 321

  Fly   275 GRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTL 339
            |:.|:|:..:::.|..|.   ...|.:.|..|....|.:.::.::.....:.|:...|.:|:..|
Mouse   322 GKTDQAWKELQRIASING---KKGIAQNLTTEDLRSKLKKDVNSTGKLFRIKDIFINPLIRKIVL 383

  Fly   340 ----LIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGT 400
                |:|.:.|    .:.||..:...||.|..:..:..||:::|..:|..||:....||.::...
Mouse   384 SNSSLLFAELF----SFVGLLLDVQLLGKNMFLTQIFLGAIDVPSKSLTYFTIRNVSRRPLIAFL 444

  Fly   401 MMVAGISLLATIFVPSDMNWLIVACAMIGK--LAITSSYGTIYIFSAEQFPTVVRNVGLGASSMV 463
            ::..|..:..|||:..:|..|.....::||  .|..:...|.||  .|..|..:|:...|....|
Mouse   445 LLTTGSCITITIFISEEMYVLRTIIFILGKGCFAAFTCISTTYI--NELSPVELRSTLNGVFLAV 507

  Fly   464 ARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE--------N 520
            .|:.|:|:.......:.:..||:|:.|.|.:.|.:..|.||||.|.|..:.|:|.|        |
Mouse   508 VRLAGVLSALTLATRKYFVYLPMILYGVLPIVATISILFLPETFNLPHTDIIKDMEKRKRLMSKN 572

  Fly   521 FGKKPAPQ--ETAE 532
            ..||....  ||.|
Mouse   573 ISKKEGQDFLETTE 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	142/559 (25%)
		MFS	135..491	CDD:119392	95/362 (26%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	112/449 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843675
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48025
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960