Protein Alignment Orct and Slc22a8

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_112471.3
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 546
• Identity: 173/546 - (31%)
• Similarity: 290/546 - (53%)
• Gaps: 23/546 - (4%)

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHL 65
            |.:.:::..:|..||:|.....||.||.:..|.|.|..:|....||..|. |..|.|   |.|
Mouse     1 MTFSEILDRVGSMGPFQYLHVTLLALPILGIANHNLLQIFTATTPDHHCR-PPPNAS---LEP-- 59

  Fly    66 WNLSYPEN---ERCSYYDVDYTEEYLNGSIPR-SSNETKTC-SSYVYDRSKYLNSAVTEWNLVCS 125
            |.|....|   |:|..:     ....|.|:|. :...|:.| ..::|:.::  ::.||||:|||.
Mouse    60 WVLPLGPNGKPEKCLRF-----VHLPNASLPNDTQGATEPCLDGWIYNSTR--DTIVTEWDLVCG 117

  Fly   126 RSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMI 190
            .:.|...:.|:||.|:|:|..:||::||:.||||....|.:|....|..||.:|....|.|.|.:
Mouse   118 SNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFL 182

  Fly   191 VGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGL 255
            .|.:.||:.|...::.:|.|.:|.|..:...:...:::|..:..|.||.:..|||||::::....
Mouse   183 CGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFF 247

  Fly   256 LFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQ 320
            :|....|.:|||.|||::.|:..:|...:::.|..|.   ..|..|:|..|..:...|.::.:::
Mouse   248 IFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNG---KKEEGEKLTVEELKFNLQKDITSAK 309

  Fly   321 PAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLL 385
            ....:.||.|...|||.|..:...||.....||.|:......|.|..:..:|.|.|:||...:.:
Mouse   310 VKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITI 374

  Fly   386 FTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPT 450
            .:::..|||......:::||:::||.|||.|:|..|..|.|:.||..::.|:..::::::|.:||
Mouse   375 LSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPT 439

  Fly   451 VVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETI 515
            |:|..|:|.|::.||||.::||.:|:.||:...:|.:|.|.::|..|..:..|.||||:|:||||
Mouse   440 VLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETI 504

  Fly   516 EDGENFGK--KPAPQETAEEGGTQEL 539
            ||.:::.:  |...||...|..:|.:
Mouse   505 EDIQDWYQQTKKTKQEPEAEKASQTI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	162/507 (32%)
Slc22a8	NP_112471.3	2A0119	11..503	CDD:273328	162/507 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		5/18 (28%)