Protein Alignment Orct and F45E10.2

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001022174.1
• Gene: F45E10.2 / 185801
• WormBaseID: WBGene00009729
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 167/536 - (31%)
• Similarity: 271/536 - (50%)
• Gaps: 82/536 - (15%)

  Fly     4 DDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNL 68
            :.:...||.||.:|:..:.|:|:|....:.|.::..|:::
 Worm    69 ESIFEGLGSFGRFQQIQFILICIPIAFVSMHVMSWTFVVS------------------------- 108

  Fly    69 SYPENERCSYYDVDYTEEYLNGSIPRSSNETKT--CSSYVYDRSKYLNSAVTEWNLVCSRSLLSA 131
              |..:.|:                 .:|||:.  |....|       ||...|.:......:.|
 Worm   109 --PARKICN-----------------ETNETRIDGCEELAY-------SASDRWEMDGDNGWIRA 147

  Fly   132 TSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTS 196
            |..:::.:|.::||...|.|:||:|||...|..||||::..:|..|||.::.|.|.:...|.|..
 Worm   148 TVQAVYFIGQMIGSFTCGVMADKIGRKKVLFWCLVLQVVCALLLIVAPTWWIYAILKAGTGFTQP 212

  Fly   197 GVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYY 261
            |::.||.|:.:|:||..||.|..|...:|..:|.:|.|..||||.|:|.|..:|.:|.|:|:.||
 Worm   213 GIYGVAVVLGIELVGKKYRSFIAVIANVFGVIGGVLLAVMAYFIVDYRLLHASIAIPSLIFITYY 277

  Fly   262 WIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPN---EIYEQLVDEVAEKKKQDEMAASQPAA 323
            |:|.||||||:.:.:.|:|.|::...|..||..:|.   |..|:.:|..|.|||.        :.
 Worm   278 WMIHESARWLVSQEKYDDANVVLCATANWNKKTIPKNWAEKIEKKMDVTATKKKD--------SF 334

  Fly   324 TVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTL 388
            .||||:|.|.:|::|:..|..|.|.:.:||||:..::..||:..|.|:.|..:|:|...::...:
 Worm   335 GVFDLIRTPQMRKRTIANFVMWPVTTMMYYGLTMRSDVGGGSLFVTFVTSQLMELPAVIIVALLI 399

  Fly   389 NRWGRRSILCGTMMVAGISLLAT----IFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFP 449
            :|.|||.:..|.:..||:.|||:    ..:||.   ..|...|:.|.|::.:|..:|.:::|.||
 Worm   400 DRLGRRIMYSGAIFTAGMLLLASWLTHDLIPSQ---YAVIMLMVAKGAVSVAYTVMYTYTSELFP 461

  Fly   450 TVVRNVGLGASSMVARVGGILAPYLKL-----LGEIWRPLPLIICGALSLTAGLLS-LLLPETLN 508
            ||:||..:|..|.:||.|.|.|.::..     .|.|...:|..|   |:|.|.::| .:||||:|
 Worm   462 TVIRNTAVGCCSTIARFGAISASFIAFFLVDRFGRIVMIIPFTI---LALCASIVSWTMLPETVN 523

  Fly   509 KPMPETIEDGENFGKK 524
            :.:|::|.:.|  |.|
 Worm   524 QQLPDSISEVE--GNK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	162/517 (31%)
F45E10.2	NP_001022174.1	MFS_SLC22	121..518	CDD:340875	142/417 (34%)