DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and Ust5r

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	560	Identity:	144/560 - (25%)
Similarity:	252/560 - (45%)	Gaps:	43/560 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALP-YENGSIYELSPH 64
            |.:.:::..:|..|.:|......:.|..:....|.....|..|.|..||.:| .:|.::.:....
  Rat     1 MAFQELLNQVGSLGRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHRCWVPILDNVTVSDNHSR 65

  Fly    65 LWN------LSYPEN-----ERC------SYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSK 111
            :.|      :|.|.:     ::|      .::.:|..:.:  .|:..:  :|:.| ..:|||||.
  Rat    66 ILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTF--SSVTEA--DTEPCVDGWVYDRSN 126

  Fly   112 YLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAA 176
            :.::.||||:|||...:|::.:...||:|..:|.::.|.:||:.|||.....:|:...|......
  Rat   127 FHSTTVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKFVLKCALLQMAITETCVG 191

  Fly   177 VAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIH 241
            .|..:|.|...|.:.|.|...:.:.:.::..|.....:.....|......|.|.|:.||.|:...
  Rat   192 FASNFFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFGSMILAGLAFQFQ 256

  Fly   242 DWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDE 306
            :|..||:|:::|...||.....:.||||||::..:..:....:.|.|..|.::...   :.|..|
  Rat   257 NWHHLQLAMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSG---DNLTME 318

  Fly   307 VAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGN-QLVNF 370
            |.....:.|:.|::...:..||...|.||::...:.|...:.....:|:|.:..:|..| .|:.|
  Rat   319 VVRTSMKRELEAAKARPSPRDLFHTPILRKRICAMSFMRILFMLSIFGMSLHLQHLSSNIMLLQF 383

  Fly   371 MISGAVEIPGYTLLLFTL------NRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIG 429
            ::|.       :.|||::      ||.|||......|.:.||.:|..:|||.:|..|.:....:.
  Rat   384 VVSA-------SSLLFSVIGPYVFNRMGRRITQMVVMTLRGICILTAVFVPQEMQILRITVVTLA 441

  Fly   430 KLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSL 494
            ......|:|...:.:.|..||.:|...:|...|....|..|||...:|......||.|..|..|:
  Rat   442 GAFSALSFGVNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFMILASYSPNLPWIFYGGFSI 506

  Fly   495 TAGLLSLLLPETLNKPMPETIED-GENFGKKPAPQETAEE 533
            ..|....|||||.|:|:|:.|.| |.::  :.:.||..|:
  Rat   507 LNGFTVFLLPETKNQPLPDCIHDIGNDW--EESRQEMKED 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	137/528 (26%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	93/362 (26%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	112/418 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940