DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and UST4r

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	558	Identity:	150/558 - (26%)
Similarity:	259/558 - (46%)	Gaps:	39/558 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALP-YENGSIYELSPH 64
            |.:.:::..:|..|.:|......:...:::...|.:...|..|.|..||.:| .:|.::.:....
  Rat     1 MAFQELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDNDSR 65

  Fly    65 LWN------LSYPEN-----ERC------SYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSK 111
            :.|      :|.|.:     ::|      .::.:|..:.:.:.:.|    :|:.| ..:|||||.
  Rat    66 ILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEP----DTEPCVDGWVYDRSN 126

  Fly   112 YLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAA 176
            :.::.||||||||....|::.:...||:|..:|.::.|.:||:.|||.....:|:...|....|.
  Rat   127 FHSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITETCAG 191

  Fly   177 VAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIH 241
            .||..|.|...|.:.|.:...:.:...::..|.....:.....|......|.|.|:.||.|:...
  Rat   192 FAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSFGGMILAGLAFQFQ 256

  Fly   242 DWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDE 306
            :|..||:|:::|...||.....:.||||||::..:..:....::|.|..|.::...   :.:..|
  Rat   257 NWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGMKKSG---DNITME 318

  Fly   307 VAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFD--WFVNSGVYYGLSWNTNNLGGN-QLV 368
            |.....:.|:.|::...:..||...|.||::..::.|.  .|:.|||  |::.:..:|..| :|:
  Rat   319 VVRTSMKKELEAAKMRPSPRDLFHTPILRKQIYILSFIRLLFILSGV--GVAIHLQHLSNNIELL 381

  Fly   369 NFMISGA---VEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGK 430
            ..:||.:   ..:.|:    |.||..|||......|.:.|||:|..||.|.:|..|....||:.:
  Rat   382 QILISVSSILFSVIGH----FVLNHIGRRITQMVIMFLRGISILTAIFAPQEMETLRFIMAMMAE 442

  Fly   431 LAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLT 495
            .....||....:.:.|..||.:|....|...|...:|..|||...:|......||.|..|..::.
  Rat   443 GLAALSYAANSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLASYSPNLPWIFYGGFAIL 507

  Fly   496 AGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEE 533
            :|.:.||||||.|.|:|:...|.||..|: :.||..|:
  Rat   508 SGFIVLLLPETKNNPLPDCTHDVENDWKE-SRQEMKED 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	142/527 (27%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	98/361 (27%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	119/419 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940