Protein Alignment Orct and SLC22A31

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 123/434 - (28%)
• Similarity: 198/434 - (45%)
• Gaps: 53/434 - (12%)

  Fly   120 WNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSY 184
            |||||.............:||.|||.:|.|...|:.||:..|.|||||....|...|:|..:.:.
Human     9 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASFPTL 73

  Fly   185 TISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQ-I 248
            .:.|::.|.|.:|..|..|:..||:....:||...:...:|..||.:|..|.|..:.|||.|| :
Human    74 LVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLLQGL 138

  Fly   249 AITLPGLLFLCYYW----IIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAE 309
            ...:.|||.|  :|    :.|||..|||..|:...|..|:.:.|:.:.|...:...|:  :.:|.
Human   139 GALMSGLLLL--FWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEE--NSLAT 199

  Fly   310 KKKQDEMAASQPAATVFDLLRYPN----LRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNF 370
            :.......:.||        ||.:    ||.:.     .|  .:|:..|.|   :.:||....:|
Human   200 ELTMLSARSPQP--------RYHSPLGLLRTRV-----TW--RNGLILGFS---SLVGGGIRASF 246

  Fly   371 MISGAVEIPGYTL---------------LLFTLNRWGRRSILCGTMMVAGISLLATI----FVPS 416
            ..|.|.::|.:.|               ||.|.:..|||.:|....||.|::.|..:    ::|
Human   247 RRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQYLP- 310

  Fly   417 DMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIW 481
              .|.::..:::|.||..:......:|:||.||||:|..|||.......:|....|...|.|...
Human   311 --GWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQG 373

  Fly   482 RPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKP 525
            ..|..::..:|::.|.|..|||||:.::.:|::::|.:...:.|
Human   374 FFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRSP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	121/421 (29%)
		MFS	135..491	CDD:119392	107/383 (28%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	112/398 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940