Protein Alignment Orct and Slc22a13

DIOPT Version :10

• Sequence 1: NP_524479.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_598741.2
• Gene: Slc22a13 / 102570
• MGIID: 2143107
• Length: 551
• Species: Mus musculus
• Alignment Length: 560
• Identity: 189/560 - (33%)
• Similarity: 301/560 - (53%)
• Gaps: 48/560 - (8%)

  Fly     3 YDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67
            :..|:..:|:||.:|.|:..|:.:|..:.||.....||::......|::.:       :..|.:|
Mouse     4 FAQVMAEVGDFGRFQVRLTILMGIPNFLAAFFIFGQVFMVLDEAHHCSVSW-------VKNHTFN 61

  Fly    68 LSYPEN-------------ERCSYYDVDYTEEYLNGSIPRSSNETKTCSS---YVYDRSKYLNSA 116
            ||..|.             |.|..:........|...:....|||:.|.|   |..:|.:.|..
Mouse    62 LSAAEQLAISIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYPENRPQSLKK- 125

  Fly   117 VTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEY 181
              |::|||.|..|..||.|:||.|:|:|:|:||.:.|.:||:|    ||::|::...:.::|..:
Mouse   126 --EFDLVCDRKNLKKTSQSVFMAGLLVGALVFGPVCDWIGRRP----SLLMQVLLSGITSMATAF 184

  Fly   182 FS----YTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHD 242
            .|    |...|.::....:|..|...|:..|.||.|:|..|.|..|...::|.|:.||.||.:.:
Mouse   185 VSSFELYLALRFVLATANAGFLLSTNVLISEWVGPSWRTQAVVLAQSNVALGQMVLAGLAYGVRN 249

  Fly   243 WRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEV 307
            ||.|||..|.|.||...|:|::|||.||||.:||.:||..:::|||..|...:..|:..|||.|
Mouse   250 WRLLQITGTAPVLLLFFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLSPELLNQLVPE- 313

  Fly   308 AEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMI 372
                      .:.|:....||.|:|:||:.||::...|||:|.|||.||:...:.|.:..|..:|
Mouse   314 ----------KTGPSGNALDLFRHPHLRKVTLILIAVWFVDSLVYYSLSFQVGDFGLDIYVTQLI 368

  Fly   373 SGAVEIPGYTLLLFTLNRWGRR-SILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSS 436
            .||||:||..|.:..:.:.||: |.|| |:.:|||..:..||:|.|:..::...|::||.|..::
Mouse   369 FGAVEMPGRFLSVLMMEKLGRKWSQLC-TLTLAGIMYIIIIFIPGDLPTVVTVLAVVGKFASAAA 432

  Fly   437 YGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSL 501
            :...|:::||.|||::|..|:|..|:.:|||||:.|.:.||.:..:.:|::|.|:|.:.||||..
Mouse   433 FTISYVYTAELFPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHQAIPMVIFGSLPIGAGLLCA 497

  Fly   502 LLPETLNKPMPETIEDGENFGKKPAPQETAEEGGTQELSG 541
            |||||..:.:.:|::|.|. |......:||.:....|..|
Mouse   498 LLPETRGQTLKDTLQDLEQ-GLPAGSHKTAPQRQDMEALG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_524479.1	2A0119	11..514	CDD:273328	180/523 (34%)
Slc22a13	NP_598741.2	2A0119	12..510	CDD:273328	180/523 (34%)