DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Orct and LOC100490946

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	531	Identity:	155/531 - (29%)
Similarity:	254/531 - (47%)	Gaps:	39/531 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCS 77
            |.|:|..:..||..|......|....||..|.|.:.|     ..::....|.     ||| :.|:
Frog    14 FSPFQAIMVTLLSAPLCFVGTHNFMPVFAAAVPPYNC-----RSNMTMDQPR-----YPE-DPCT 67

  Fly    78 YYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGV 141
            .|            :...||.||.| ..:.||.|.:.::.::||:|||.|..|...:.|::|.||
Frog    68 QY------------VSSLSNSTKPCEEGWEYDHSIFTSTIISEWDLVCDRQTLKEVAQSVYMAGV 120

  Fly   142 LLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIA 206
            |:|:.::|.::|:.||:.....||:.....|:..|::|....|.:.|.:.|....|:.:....:|
Frog   121 LVGAAVYGALADRFGRRAMILCSLLQIAGMGIGVALSPNIIVYCLFRFLTGMGICGLIINDLGLA 185

  Fly   207 LEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWL 271
            :|.....||....:......:.|.::..|.||.|..|||||:..:||..:|......:|||||||
Frog   186 MEWTPRRYRPIVSMIQGYGLTCGAIILVGLAYAIRGWRWLQLTASLPYFIFFLLMCWVPESARWL 250

  Fly   272 LMKGRKDEAFVIIEKAAKEN--KVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNL 334
            .:|...::|...:.:.||.|  |...|      :..|:.:...|....|.....|..||.|.|.:
Frog   251 SLKKHSNQALANLNRVAKINGRKEGGP------ITLEMLKLDDQHSTKAMTTKLTPLDLFRTPTM 309

  Fly   335 RRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCG 399
            |..||::...||.:|..::.::.:.:..|.:..:...:....|:|...|...|....|||..:..
Frog   310 RTITLILSLSWFSSSFGFFAIALDVDRFGLSLYLTQGVFAGSELPIRILATITAFYIGRRLTISF 374

  Fly   400 TMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVA 464
            .::.||..||.|:.||.||..|.:...::.|.::.|.....|:::||.:|||:|..|||.::|:.
Frog   375 LLIFAGTLLLCTMAVPKDMLLLQMILTVLAKASLGSCIVCSYLYTAEVYPTVLRQTGLGFTNMMM 439

  Fly   465 RVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGE------NFGK 523
            |:|.|::|.:.:.......||::|...:.:.:||..||||||||.|:.:|:|:.|      ||..
Frog   440 RLGAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILLLPETLNCPLMDTVEEVESRNRELNFQI 504

  Fly   524 KPAPQETAEEG 534
            | .|:|.:..|
Frog   505 K-IPKENSGPG 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	146/503 (29%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	102/357 (29%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010