DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	541	Identity:	172/541 - (31%)
Similarity:	281/541 - (51%)	Gaps:	14/541 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALP-YENGSIYELSPH 64
            ||::|::..:|..|.:|.....:|.:|.:....|.....|..|.|..||.:| .:|.::.....|
Frog     1 MGFNDLLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDH 65

  Fly    65 L-WNLSYPENER---CSYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLNSAVTEWNLVC 124
            | ..:...|:|:   |..|.......:.||:   |:|.|:.| ..:|||:|.:.::.||||:|||
Frog    66 LPAFIPMDESEKPLSCLRYRKALHSMWTNGT---STNHTEPCEDGWVYDKSDFSSTIVTEWDLVC 127

  Fly   125 SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRM 189
            ....:...:.|::|.|||:|:::.|.:||:|||:.....|.::..:.|..||..|.:.:|...|.
Frog   128 KLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCTFRC 192

  Fly   190 IVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPG 254
            :.|...||:.|....:.||......|...|......|:.|.:|.|..||.|.:|||||.|::.|.
Frog   193 LCGIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTCGQILLAALAYGIREWRWLQFAVSAPF 257

  Fly   255 LLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAAS 319
            ..|..|.|::|||||||::|||..||...:::.|..|.   ..|..::|.:.:.....|.|:...
Frog   258 YFFFLYSWLVPESARWLILKGRSHEALKALQRVAIING---KREEGQKLSEMILISHMQSELNQV 319

  Fly   320 QPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLL 384
            :...::|||.|.|.:|:.|:.:...||.:...:|||..:..|.|.:..:.....||:::|...:.
Frog   320 KRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFGISIFLLQFTFGAIDMPAKVVA 384

  Fly   385 LFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFP 449
            ...:...|||......::::|::||...|:|..|..|.:..|:.||..:.:|:...|:||.|.||
Frog   385 ALLMTYMGRRVTQATVLILSGVALLTNAFIPQGMKILRMVLAVFGKGCMAASFACAYLFSGELFP 449

  Fly   450 TVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPET 514
            ||:|..|:|..:|:||||.::||.:.||.||...||..|.|..::.||..:..|.||.|:.:||:
Frog   450 TVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAIYGIAAIIAGGAATFLMETNNQQLPES 514

  Fly   515 IEDGE--NFGKKPAPQETAEE 533
            :|:.|  :.||....:...||
Frog   515 VEEVEARSQGKHTLKKVLKEE 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	162/508 (32%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	118/355 (33%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	128/386 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm14089
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010