Protein Alignment Orct and sv2a

DIOPT Version :9

• Sequence 1: NP_001262908.1
• Gene: Orct / 42891
• FlyBaseID: FBgn0019952
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 100/545 - (18%)
• Similarity: 190/545 - (34%)
• Gaps: 179/545 - (32%)

  Fly   133 SDS-------LFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMI 190
            |||       :..||:::|:.::|.|:|::||:.....||.:..:|...::....|.::...|::
 Frog   187 SDSNKGMLGLIVYLGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLL 251

  Fly   191 VGATTSGVFLVAY-----VIALE-------------MVGSSYRLFAGVAMQMFFSVGFMLTAGFA 237
            .|....|...:.:     .:|.|             |:|..|.  :.:|..:....|:....|.|
 Frog   252 SGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGIYA--SAMAWAIIPHYGWSFQMGSA 314

  Fly   238 YFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEV--PNEIY 300
            |..|.||...:....|.:..:.....:|||.|:.|..|:.|||::::::....|....  |..::
 Frog   315 YQFHSWRVFVLVCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVF 379

  Fly   301 EQLVDEVAEKKKQDEMA-------------------ASQPAATVFDLLRYPNLRRKTLLIFFDWF 346
            .  |.::...|:.||:.                   .||.....|.....|..||.||::...||
 Frog   380 S--VTQIKTIKQDDELVEIQSDTGALHRRWMIKLLNLSQEVWANFHQCFAPEYRRITLMMMAVWF 442

  Fly   347 VNSGVYYGLS-W-----------------------NTNNLG------------------------ 363
            ..|..||||: |                       :.||..
 Frog   443 TMSFSYYGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFTLENQVHRKGEYHNDKFIGLK 507

  Fly   364 -------------------------------------------------------------GNQL 367
                                                                         |.||
 Frog   508 LKSVIFEDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYKFINSKFTNSTFLHSKEGCQL 572

  Fly   368 --------------VNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDM 418
                          |:|:.:.|| :||..:....:::.||..:|.|:.:::.||.....|..|:.
 Frog   573 DFSDDINNAYMIYFVSFLGTLAV-LPGNIVSALLMDKIGRLRMLAGSSVMSCISCFFLFFGNSES 636

  Fly   419 NWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGIL--APYLKLLGEIW 481
            ..:.:.| :.|.::| :|:..:.:.:.|.:|:..|....|..:.:.::..:|  :.:...:| :.
 Frog   637 AMIALLC-LFGGVSI-ASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVG-VA 698

  Fly   482 RPLPLIICGALSLTAGLLSLLLPET 506
            :.:|:::..|.......|:|.||||
 Frog   699 KAVPILLASAALAVGSFLALKLPET 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	100/545 (18%)
		MFS	135..491	CDD:119392	91/526 (17%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	100/545 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940