Protein Alignment Orct2 and TPO2

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_011654.1
• Gene: TPO2 / 853039
• SGDID: S000003370
• Length: 614
• Species: Saccharomyces cerevisiae
• Alignment Length: 569
• Identity: 108/569 - (18%)
• Similarity: 192/569 - (33%)
• Gaps: 186/569 - (32%)

  Fly    67 NLSYPENERCSYYDVDYTEEYLNGSIPRSSNET--KTCSSYVYDRSKYLNSAVT----------- 118
            :::.|:..:.:.:..:||.|..:|.:|.::.::  :|.|:....|:|.||...|
Yeast    64 DINAPQTAKNNIFPEEYTMETPSGLVPVATLQSMGRTASALSRTRTKQLNRTATNSSSTGKEEME 128

  Fly   119 ----------------------------------------EWN--------LVC----------- 124
                                                    .|:        ::|
Yeast   129 EEETEEREDQSGENELDPEIEFVTFVTGDPENPHNWPSWVRWSYTVLLSILVICVAYGSACISGG 193

  Fly   125 ----------GRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAP 179
                      |.: .|..|.||.::|..||.:::..:||.|||:...|.|:.:.|:|.:...:||
Yeast   194 LGTVEKKYHVGME-AAILSCSLMVIGFSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAP 257

  Fly   180 EYFTYTFARLMVGA-TTSGVFLV-----------------AYVVAMEMVGPDKRLYAGIFVMMFF 226
            ........|.:.|. ::||:.||                 |:......|||    ..|..|..|.
Yeast   258 NLGCLLACRFLCGVWSSSGLCLVGGSIADMFPSETRGKAIAFFAFAPYVGP----VVGPLVNGFI 318

  Fly   227 SVGF-MLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWI----IPESARWLLLKGRKDCAIANMQK 286
            ||.. .:..:|        |:.:|       |....||    |||:...::||          :|
Yeast   319 SVSTGRMDLIF--------WVNMA-------FAGVMWIISSAIPETYAPVILK----------RK 358

  Fly   287 AARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLL--IFL 349
            |||..|...:.:.::|...:|.:..|..:..|. :.|.......|....|:......:||  .|.
Yeast   359 AARLRKETGNPKIMTEQEAQGVSMSEMMRACLL-RPLYFAVTEPVLVATCFYVCLIYSLLYAFFF 422

  Fly   350 DWLVTSGVYYGLSWNTSNLGGNVLLNFVIS-------------------------------GA-V 382
            .:.|..|..||..   .||.|.:.:..||.                               || :
Yeast   423 AFPVIFGELYGYK---DNLVGLMFIPIVIGALWALATTFYCENKYLQIVKQRKPTPEDRLLGAKI 484

  Fly   383 EIPAYIFLLLTLNRWGRRSILCGCLVMAGLSL-LATVIIPQRMHTLIVAC-------AMLGKLAI 439
            ..|.....|..|.....:.|:......|||:. ...|:|...::..|:.|       |:..|:.:
Yeast   485 GAPFAAIALWILGATAYKHIIWVGPASAGLAFGFGMVLIYYSLNNYIIDCYVQYASSALATKVFL 549

  Fly   440 TASYGTVY-IFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIW 487
            .::.|..: :|:.:.:..:  |:..|:..:....:.|:|  |.|..:.|
Yeast   550 RSAGGAAFPLFTIQMYHKL--NLHWGSWLLAFISTAMIA--LPFAFSYW 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	108/569 (19%)
TPO2	NP_011654.1	MFS_Tpo1_MDR_like	173..599	CDD:340881	94/460 (20%)