Protein Alignment Orct2 and GIT1

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_010022.1
• Gene: GIT1 / 850462
• SGDID: S000000695
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 513
• Identity: 88/513 - (17%)
• Similarity: 160/513 - (31%)
• Gaps: 170/513 - (33%)

  Fly    73 NERCSYYDVDYTEEYLNGSIPRSSNETKT-------------CSSYVYDRSKYLNSAVTEWNLVC 124
            |.|...||.:           |.:..|:|             .|.:......|:|.:::..|.|.
Yeast    19 NPRIIKYDAE-----------RRATRTETSKKDKWKNIVTIIASGFALISDGYVNGSMSMLNKVF 72

  Fly   125 GRDF--------MAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLA------ 175
            ..::        ::....:..::|::.|....|..:|.|.||..:..:..|.|:...|.
Yeast    73 VMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGT 137

  Fly   176 ------------------GVAPEYFTYTF-----ARLMVGATTSGVFLVAYVVAMEMVGPDKRLY 217
                              ||..||.|.|.     |.........|:.::...:.:...||...:
Yeast   138 TVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATI- 201

  Fly   218 AGIFVMMF----------------FSVG-FMLTAVFAYFVHDWRWL----------QIALTLPGL 255
              ||::::                |::| |...:|| ||    ||.          :|...:|..
Yeast   202 --IFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVF-YF----RWKTATTEVYEKGRIKRNIPYF 259

  Fly   256 IFMFYYW--IIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKL 318
            :.:.:||  ::.....|.            |.....|.....|...:|.::.: :|...|..:
Yeast   260 LALKFYWKRLLGTCGTWF------------MYDFVTFPNGIFSSTIISSVIKD-QNDLVKVAE-- 309

  Fly   319 EDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVE 383
                         |:|             .|..|...||..| ::.:..:|....|.|..||
Yeast   310 -------------WNL-------------LLGVLAVLGVPIG-AYLSDRIGRKYTLMFGFSG--- 344

  Fly   384 IPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITASYGTVYI 448
               ||..          .::.||         |...:.:.....|:..|.:..|........:.:
Yeast   345 ---YIIF----------GLIIGC---------AYDQLKKITPLFIIFYAFMNMLGNAGPGDMLGV 387

  Fly   449 FSAEQFPTVVRNVALGAASMVARISGMMA-----PFLNFLATIWKPLPLLICGSLTLV 501
            .|:|...|.||.|..|.:::..:|..::.     |..:.|...|..:...|||.:.::
Yeast   388 ISSEASATAVRGVFYGLSAVTGKIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGII 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	88/513 (17%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	81/473 (17%)