Protein Alignment Orct2 and slc22a21

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001295487.1
• Gene: slc22a21 / 799908
• ZFINID: ZDB-GENE-091118-62
• Length: 546
• Species: Danio rerio
• Alignment Length: 541
• Identity: 190/541 - (35%)
• Similarity: 298/541 - (55%)
• Gaps: 46/541 - (8%)

  Fly     3 YDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWN 67
            |:|....||.:|.:||.::.|:||:.||..|..|:.|||...|...|.:|    .:.:|.....|
Zfish     6 YEEQTAFLGAWGPFQKTVFSLLCLSIIPNGFTGLSIVFLGDTPAHHCRIP----ETLNLTAGWRN 66

  Fly    68 LSYPENE--------RCSYYDVDYTEEYLNG-----------SIPRSSNETKTCSSYVYDRSKYL 113
            .|.|..:        ||....:|..:.|.:|           .|||.    :....::||:..|.
Zfish    67 ASVPRPQPHGDPRASRCYRLRLDLVKNYSDGGLLPGLDVNVSEIPRE----ECADGWIYDKEIYS 127

  Fly   114 NSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVA 178
            ::.|:||:|||..|:.:..:.|:|..|||.||::.|.:||::|||.:||.::.||.||.|:...:
Zfish   128 STIVSEWDLVCSDDWKSPLTSSIFFCGVLTGSVISGPVSDRFGRKIVLFVTMAIQTLFTVVQVFS 192

  Fly   179 PEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKR-LYAGIFVMMFFSVGFMLTAVFAYFVHD 242
            |.:..:.|...:||......::.|:|:.||::....| :|:.:.|.:|||:|:|:..:.|:|:.|
Zfish   193 PSWQIFCFLFFIVGMGQISNYVAAFVLGMEILSSSVRDVYSTLGVCLFFSIGYMILPLAAFFLRD 257

  Fly   243 WRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEG 307
            ||.|.:|||:||..::..:|.||||.||||.:||...|.|.::|||:.|:|...| .:..|:...
Zfish   258 WRSLMLALTIPGFFYIPLWWFIPESPRWLLSQGRVQEAEAIIRKAAKINRVTAPD-VIFPLMQST 321

  Fly   308 ENSEEKAKQKLEDQELDEGPPP--SVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGG 370
            |               |.|...  ||.:|....|:|..|.|:.|.|:..|..|..||.|||:|.|
Zfish   322 E---------------DAGGVQSFSVCELLKSSNIRYMTGLLCLIWMAVSIGYCALSLNTSSLHG 371

  Fly   371 NVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLG 435
            |:.||.::|..||:||.:...|.|....||..|...|.:.||.||..::||:...::.:|..|||
Zfish   372 NIYLNCLLSAVVEVPALLMAWLMLRLAPRRHCLASTLALGGLVLLLILLIPEDQSSVTLALVMLG 436

  Fly   436 KLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTL 500
            |..::|::..:|..:||.:|||:||.||||.||.:|:.|:.||:.|:|.:..:.||.::.|.:.:
Zfish   437 KFGLSAAFSIIYPVTAELYPTVLRNTALGACSMSSRVGGISAPYFNYLGSYHRSLPYILIGGINV 501

  Fly   501 VAGLLSLLLPETHNKPMLETI 521
            ::||||.||||:....:.|||
Zfish   502 LSGLLSFLLPESRGSALPETI 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	184/530 (35%)
		MFS	127..503	CDD:119392	138/378 (37%)
slc22a21	NP_001295487.1	2A0119	14..521	CDD:273328	184/530 (35%)
		MFS	146..511	CDD:119392	142/380 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100389
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.840