Protein Alignment Orct2 and slc22a15.2

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001039179.1
• Gene: slc22a15.2 / 734018
• XenbaseID: XB-GENE-5824718
• Length: 487
• Species: Xenopus tropicalis
• Alignment Length: 565
• Identity: 172/565 - (30%)
• Similarity: 269/565 - (47%)
• Gaps: 82/565 - (14%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHL 65
            |..|||.:::|:||..||.:...:.|..:.||...:..|.:.|.|::..
 Frog     1 MDLDEAFLYIGEFGCCQKRLTAFLTLLQVYVACQSMLIVLVGAVPEYLI---------------- 49

  Fly    66 WNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMA 130
                  :||..|....:||:                   :::|.:.: .|.|:||:|:....:..
 Frog    50 ------DNEDISASKEEYTK-------------------HLHDTNNF-TSIVSEWHLIKNEAYKV 88

  Fly   131 ATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATT 195
            ..:.|||..|:|:|:|:||.||||.||:|:..:.|...:.||....:||.|..:..:|..||...
 Frog    89 NLASSLFFAGLLIGNILFGPLSDKLGRRPVYLSGLFFDITFGYCTALAPSYEVFAVSRFFVGIMN 153

  Fly   196 SGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFY 260
            .|:.||::|:..|.||.......|....:.|:||....|:..:::.:||.|......||:.|...
 Frog   154 GGMALVSFVLTQEYVGKSYWALTGSLTNLIFAVGIAFYALLGFYIRNWRTLAFVANSPGIFFFLL 218

  Fly   261 YWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDE 325
            .:::|||.|||...|....|...:|..|..|.||   ..:.:|......|.:.|.
 Frog   219 SFLLPESPRWLYSHGYTTEAEGVLQSMAVGNGVE---RPVVKLKSCPGTSSKSAH---------- 270

  Fly   326 GPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFL 390
                ||:||..|..||.:|:|:...|.|.|.|||||:.|...|.||:.||..:.|.||:||:...
 Frog   271 ----SVFDLVKYGVLRWRTILLMYIWYVCSLVYYGLTLNAGELKGNLYLNVALYGLVEVPAFPLC 331

  Fly   391 LLTLNR-W-GRRSILCGCLVMAGLSLLATVIIPQRMHTLI--VACAMLGKLAITASYGTVYIFSA 451
            |..:.: | |||....|.|..||.:.:.|:.:|:....|:  ...|:.|||:::|::..|||:::
 Frog   332 LYFIEKSWSGRRKATAGFLGFAGFACIFTIFLPETNGDLLNPTVLALFGKLSVSAAFNVVYIYTS 396

  Fly   452 EQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKP 516
            |.:||||||..||..:|..|..|:::||:..:.::...:|.:..|...:.||:||||||||.|||
 Frog   397 ELYPTVVRNAGLGVCAMACRFGGILSPFIPTMKSLNPSMPFVAFGISGISAGILSLLLPETRNKP 461

  Fly   517 MLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSGETNGST 561
            :.|:|.|                   |::|..|.|....|...||
 Frog   462 IAESIED-------------------LQSPAYQLLSRGNEVLAST 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	158/512 (31%)
slc22a15.2	NP_001039179.1	MFS	48..455	CDD:475125	140/465 (30%)