Protein Alignment Orct2 and Slc22a16

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 576
• Identity: 180/576 - (31%)
• Similarity: 286/576 - (49%)
• Gaps: 63/576 - (10%)

  Fly     9 HLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALP-------FENGSSYDL----- 61
            |:|.|||:|.::|.:....|:....|.|:.|||...|:..|..|       |.|.|::.|
Mouse    12 HIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLEDILA 76

  Fly    62 ---PTH------------LWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSK 111
               |.|            :|.|:     |||....:.| .:|........:::.....||||:||
Mouse    77 LRSPEHKDHIMVELQDGEIWELT-----RCSRTWRENT-SHLGYEYSGYKHDSPCFDGYVYDQSK 135

  Fly   112 YLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAG 176
            :.||||..:||||.:.:.|.....|.:.||:||||.|..|||::||:..|:.:.:....||:.:.
Mouse   136 WRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASL 200

  Fly   177 VAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVH 241
            ...:|.::...|..:...:||.|:|.:|..||::|...|.:|.|.:..||::|.||.|:.:|.:.
Mouse   201 FIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLK 265

  Fly   242 DWRWL-QIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLD 305
            .| || ||.|.:....|:...|::||:..|||.:||...|...:...|.:||....|  |.|||.
Mouse   266 TW-WLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCD--LVELLS 327

  Fly   306 -EGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLG 369
             :...|..|:...:....|.        |||...::.:.||:::|||...:..||..........
Mouse   328 LDVTRSHNKSPHSIRKHRLA--------DLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRK 384

  Fly   370 GNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAML 434
            .|..|..::.||:||||||.|.:.|.|.|||..:...|:::.|:.:..|::|....|.....|:|
Mouse   385 ENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALL 449

  Fly   435 GKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLT 499
            .|..|::.:..:|:::||.:||.||.:|:|:::||:.:|.:..||.:..:.:|..||.::.|.|.
Mouse   450 VKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILA 514

  Fly   500 LVAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSG 555
            :::|||||.||||.:.||..|                .|| .|.:.||.:...|.|
Mouse   515 ILSGLLSLKLPETQDTPMKST----------------WET-TEQQVPENKDSLGEG 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	171/537 (32%)
		MFS	127..503	CDD:119392	118/377 (31%)
Slc22a16	NP_081848.1	2A0119	14..535	CDD:273328	171/537 (32%)
		MFS	163..525	CDD:119392	121/372 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		10/41 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.880